Description
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Product Unit Size | Cost | Quantity | Stock |
|---|
BAY-1895344 is an inhibitor of ataxia telangiectasia and Rad3-related kinase (ATR), a chromatin-remodeling protein that senses DNA damage and activates the DNA damage checkpoint to induce cell cycle arrest.
| Cas No. | 1876467-74-1 |
|---|---|
| Purity | ≥99% |
| Formula | C20H21N7O |
| Formula Wt. | 375.44 |
| IUPAC Name | 2-[(3R)-3-Methyl-4-morpholinyl]-4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine |
| Synonym | BAY 1895344, BAY1895344 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Wengner A., Siemeister G. et al. ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models. 77(13 Suppl):Abstract nr 836 (2017).
PI3K and mTOR inhibitor.
Glycopeptide, vancomycin analog; peptidoglycan ...
MAGL inhibitor.
Mycotoxin produced by Aspergillus and Penicillu...
Peptide toxin found in Conus snails; nAChR inhi...
PI3K inhibitor, microtubule polymerization inhi...
Synthetic ghrelin analog; ghrelin agonist.
Phytoalexin, indole found in cruciferous vegeta...
Neuropeptide found in crustaceans and insects.<...
Benzazepine derivative; D1 partial agonist, pot...
4-Hydroxytamoxifen prodrug; FIASMA, SERM, PKC i...
BRD2/3/4 inhibitor.
p110α PI3K inhibitor.
Commercial food additive, antioxidant.
Synthetic analog of 1,4-naphthoquinone, precurs...
Endogenous peptide, involved in stress signalin...
Endogenous peptide hormone, involved in feeding...
Polyene macrolide; ergosterol inhibitor.
c-Raf inhibitor, tyrosine kinase inhibitor.
Sulfur analog of furan found in cooked meat pro...