Description
7-Aminoactinomycin D (7AAD) binds DNA sequences and is used in cellular assays to measure apoptosis and phagocytosis.
7-Aminoactinomycin D
Product ID A4930
Cas No. 7240-37-1
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 7240-37-1 |
|---|---|
| Purity | ≥98% |
| Formula | C62H87N13O16 |
| Formula Wt. | 1270.43 |
| Chemical Name | 2,7-diamino-4,6-dimethyl-3-oxo-N,N'-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide |
| IUPAC Name | 2,7-diamino-4,6-dimethyl-3-oxo-1-N,9-N-bis[7,11,14-trimethyl-2,5,9,12, 15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11, 14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide |
| Synonym | 7-Amino-Actinomycin D 7-amino-AMD Actinomycin D, 7-amino- |
| Melting Point | 250°C |
| Solubility | Soluble in ethanol |
| Appearance | Purple Powder |
Shipping and Storage
| Store Temp | 4°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Su YJ, Cheng TT, Chen CJ, et al. The association among leukocyte apoptosis, autoantibodies and disease severity in systemic lupus erythematosus. J Transl Med. 2013 Oct 19;11:261. PMID: 24138706.
Ortega E, Algarra I, Serrano MJ, et al. The use of 7-amino-actinomycin D in the analysis of Candida albicans phagocytosis and opsonization. J Immunol Methods. 2001 Jul 1;253(1-2):189-93. PMID: 11384680.
Philpott NJ, Turner AJ, Scopes J, et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood. 1996 Mar 15;87(6):2244-51. PMID: 8630384.