Description
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
Product Unit Size | Cost | Quantity | Stock |
---|
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
Cas No. | 125-84-8 |
---|---|
Purity | ≥98% |
Formula | C13H16N2O2 |
Formula Wt. | 232.28 |
Chemical Name | 3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
IUPAC Name | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
Synonym | Aminoglutethimide, Cytadren, Elipten, Orimeten |
Melting Point | 149-150°C |
Solubility | Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. |
Appearance | White Crystalline Powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.
Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.
Ansamycin; bacterial DNA-dependent RNA polymera...
Semi-synthetic avermectin; GABA potentiator.
p110β PI3K inhibitor.
Furanolactone found in Citrus.
Alpha blocker and vasoactive agent.
Modifies microvascular function
Endogenous neuropeptide, somatostatin analog; s...
ITC, erucin analog.
Diterpene found in coffee beans.
Nucleoside (deoxyuridine) analog; DNA chain ter...
ITC found in Nasturtium officinale (watercress)...
Endogenous APP peptide cleavage product, primar...
Nucleoside (deoxycytidine) analog; DNMT inhibit...
Inhibitor of VEGFR and FGFR.
Organosulfur found in garlic.
Neuroprotective flavonoid
Calcitonin-family peptide frgament, involved in...
Acyl transfer catalyst, involved in peptide syn...
Fatty acid found in dairy products; HDAC inhibi...
Nucleoside (thymidine) analog; DNA chain termin...