Description
Alloxan is an oxygenated pyrimidine and toxic analog of glucose. Alloxan destroys β cells and is used in research models to induce diabetes. This compound does not affect human cells.
Product Unit Size | Cost | Quantity | Stock |
---|
Alloxan is an oxygenated pyrimidine and toxic analog of glucose. Alloxan destroys β cells and is used in research models to induce diabetes. This compound does not affect human cells.
Cas No. | 2244-11-3 |
---|---|
Purity | ≥98% |
Formula | C4H2N2O4 • H2O |
Formula Wt. | 160.08 |
Chemical Name | 2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate |
IUPAC Name | 5,5-dihydroxy-1,3-diazinane-2,4,6-trione |
Synonym | Alloxan |
Melting Point | 255°C |
Solubility | Soluble in water. |
Appearance | Tan Powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Franzén S, Friederich-Persson M, Fasching A, et al. Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes. Am J Physiol Renal Physiol. 2014 May 15;306(10):F1171-8. PMID: 24623147.
Tyrberg B, Andersson A, Borg LA. Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan. Gen Comp Endocrinol. 2001 Jun;122(3):238-51. PMID: 11356036.
Eizirik DL, Pipeleers DG, Ling Z, et al. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9253-6. PMID: 7937750.
Snake venom cardiotoxin found in Naja naja atra...
Naphthodianthrone found in Hypericum; dopamine ...
Alkaloid found in Catharanthus, precursor in sy...
Potential PKD binding agent.
Alters intracellular glutathione levels.
NSAID; COX-1/2 and lipoxygenase inhibitor.
Endogenous tachykinin peptide, involved in infl...
FIASMA, μOR agonist, potential HCN channel blo...
Component of Frankincense resin.
Impurity of diclofenac
Catechol-type flavonoid.
FIASMA; α1- and β1/2-adrenergic antagonist.
Endogenous quaternary ammonium, required for fa...
Expectorant.
Kv7 K+ channel activator, NMDA antagonist, GABA...
Fluoroquinolone, optically active isomer of ofl...
Coumarin; VKORC1 inhibitor.
Recombinant protein containing Treponema pallid...
Endogenous peptide, involved in vasoconstrictio...
Synthetic ITC, erucin analog.