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β-Zearalanol is a mycotoxin that has structural similarity to estrogen and can bind to estrogen receptors. β-Zearalanol is one of the major metabolites of zearalenone, which is produced by several species of Fusarium and is known to induce many toxic effects.
| Cas No. | 42422-68-4 |
|---|---|
| Purity | ≥98% |
| Formula | C18H26O5 |
| Formula Wt. | 322.40 |
| Chemical Name | 2,4-Dihydroxy-6-(6|A,10-dihydroxyundecyl]benzoic acid |I-lactone |
| IUPAC Name | (4~{S},8~{S})-8,16,18-trihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-2-one |
| Synonym | beta-Zearalanol, Taleranol, Teranol; Taleranolum; (3S,7S)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one; (3S,7S)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10,11,12-decahydro-1H-2-benzoxacyclotetradecin-1-one |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Tatay E, Espin S, Garcia-Fernandez AJ, et al. Estrogenic activity of zearalenone, α-Zearalenol and β-Zearalenol assessed using the E-screen assay in MCF-7 cells. Toxicol Mech Methods. 2018 May;28(4):239-242. PMID: 29057713.
Ben Salem I, Boussabbeh M, Pires Da Silva J, et al. SIRT1 protects cardiac cells against apoptosis induced by zearalenone or its metabolites α-Zearalenol and β-Zearalenol through an autophagy-dependent pathway. Toxicol Appl Pharmacol. 2017 Jan 1;314:82-90. PMID: 27889531.
