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β Melanocyte-stimulating hormone (β MSH) is an endogenous POMC-derived peptide in the pituitary involved in energy homeostasis that activates melanocortin receptors. β MSH exhibits anti-inflammatory and anorexigenic activities. In vivo, β MSH decreases the intensity of acetaminophen-induced liver lesions. In other animal models, this peptide increases orexin and corticotropin-releasing factor (CRF) levels and decreases food intake.
| Cas No. | 17908-57-5 |
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| Purity | ≥98% |
| Formula | C118H174N34O35S |
| Formula Wt. | 2660.9 |
| IUPAC Name | L-Alanyl-L-α-glutamyl-L-lysyl-L-lysyl-L-α-aspartyl-L-α-glutamylglycyl-L-prolyl-L-tyrosyl-N5-(diaminomethylene)-L-ornithyl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-N5-(dia minomethylene)-L-ornithyl-L-tryptophylglycyl-L-seryl-L-prolyl-L-prolyl-L-lysyl-L-aspartic acid |
| Synonym | β-MSH |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Blagaić V, Houra K, Turcić P, et al. The influence of alpha-, beta-, and gamma-melanocyte stimulating hormone on acetaminophen induced liver lesions in male CBA mice. Molecules. 2010 Mar 3;15(3):1232-41. PMID: 20335976.
Kamisoyama H, Honda K, Saneyasu T, et al. Corticotropin-releasing factor is a downstream mediator of the beta-melanocyte-stimulating hormone-induced anorexigenic pathway in chicks. Neurosci Lett. 2009 Jul 24;458(3):102-5. PMID: 19393716.