Description
1,2,3,4,5,6-hexabromocyclohexane directly inhibits a pocket within the JAK2 kinase domain, inhibiting autophosphorylation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
1,2,3,4,5,6-hexabromocyclohexane directly inhibits a pocket within the JAK2 kinase domain, inhibiting autophosphorylation.
| Cas No. | 1837-91-8 |
|---|---|
| Purity | ≥98% |
| Formula | C6H6Br6 |
| Formula Wt. | 557.54 |
| IUPAC Name | 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sandberg E., Ma X., et al. Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophosphorylation [correction of autophophorylation]. J Med Chem. 48(7):2526-33 (2005). PMID: 15801842.
Stearoyl-coA desaturase 1 inhibitor.
Vitamin A metabolite, differentiation inducer; ...
μOR and δOR agonist, D2/D3 DA potentiator.
Integrase inhibitor.
Macrolide; F1F0 ATP synthase inhibitor.
ITC, used as chiral agent.
JAK2 inhibitor, potential EGFR inhibitor.
Steroidal jerveratrum alkaloid found in Veratru...
Tripeptide, used to tag proteins.
Alkaloid compound originally found in Corydalis...
Prodrug of the compound mycophenolic acid.
Allosteric inhibitor
ITC found in cruciferous vegetables, analog of ...
Triterpene glycoside found in Glycyrrhiza; 11β...
Alkylphospholipid analog; Akt inhibitor.
SK K+ channel blocker, EGFR inhibitor.
Endogenous peptide hormone, involved in intesti...
Cdc7 inhibitor.
D2 agonist, NMDA, 5-HT3, α7 nAChR antagonist.<...
Endogenous opioid peptide; μOR agonist.