Description
1,2,3,4,5,6-hexabromocyclohexane directly inhibits a pocket within the JAK2 kinase domain, inhibiting autophosphorylation.
| Product Unit Size | Cost | Quantity | Stock |
|---|
1,2,3,4,5,6-hexabromocyclohexane directly inhibits a pocket within the JAK2 kinase domain, inhibiting autophosphorylation.
| Cas No. | 1837-91-8 |
|---|---|
| Purity | ≥98% |
| Formula | C6H6Br6 |
| Formula Wt. | 557.54 |
| IUPAC Name | 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sandberg E., Ma X., et al. Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophosphorylation [correction of autophophorylation]. J Med Chem. 48(7):2526-33 (2005). PMID: 15801842.
Selective inhibitor of the γ isoform of PI3K (...
Endogenous peptide, involved in vascular contra...
Potential AhR binding agent.
Metabolite of clofibrate; PPARα agonist.
Peptide, neurotensin analog.
EGFR inhibitor.
mTOR inhibitor.
VEGFR2, PDGFR, FGFR2 inhibitor.
Nitroimidazole; DNA synthesis inhibitor.
Iridoid glycoside found in Gardinia jasminoides...
p110α PI3K inhibitor.
Sulforaphane homolog, ITC found in cruciferous ...
Aminopropyl carbazole, neuroprotective.
p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR...
NSAID; COX-1/2 and PDE inhibitor.
Endogenous sphingosine-based lipid, component o...
Steroid produced by Penicillum; PI3K, mTOR, DNA...
Synthetic steroid, contraceptive; PR and glucoc...
Synthetic derivative of glycyrrhizin; connexin ...
α2-adrenergic and imidazoline-1 antagonist, AT...