Description
5-Aminopyrimidine is a useful building block in preparation of several biologically active analogs.
5-Aminopyrimidine
Product ID A016495
Cas No. 591-55-9
Purity ≥98%
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Product Info
| Cas No. | 591-55-9 |
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| Purity | ≥98% |
| Formula | C4H5N3 |
| Formula Wt. | 95.11 |
| Chemical Name | 5-Aminopyrimidine |
| IUPAC Name | Pyrimidin-5-amine |
| Synonym | pyrimidin-5-amine; 5-pyrimidinamine; PYRIMIDIN-5-YLAMINE |
| Melting Point | 171-173°C |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Xu Y, Liu X, Chen X, et al. Directed evolution of a nonheme diiron N-oxygenase AzoC for improving its catalytic efficiency toward nitrogen heterocycle substrates. Molecules. 2022 Jan 27;27(3):868. PMID: 35164125.
Elkamhawy A, Paik S, Hassan A, et al. Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide: a novel EGFR inhibitor from a designed small library. Bioorg Chem. 2017 Dec;75:393-405. PMID: 29102722.
Wong F, Huang Y, Chang C. Evaluation of electrophilic heteroaromatic substitution: synthesis of heteroaromatic-fused pyrimidine derivatives via sequential three-component heterocyclization. J Org Chem. 2012 Oct 5;77(19):8492-8500. PMID: 22950851.
Okada M, Yoden T, Kawaminami E, et al. Studies on aromatase inhibitors. IV. Synthesis and biological evaluation of N,N-disubstituted-5-aminopyrimidine derivatives. Chem Pharm Bull (Tokyo). 1997 Aug;45(8):1293-1299. PMID: 9301028.