Description
GSK-343 is an inhibitor of enhancer of zeste homolog 2 (EZH2) histone methyltransferase (HMT). GSK-343 exhibits anticancer activity, inhibiting cell invasion and cell growth in epithelial ovarian cancer cells.
GSK-343
Product ID G7442
Cas No. 1346704-33-3
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 1346704-33-3 |
|---|---|
| Purity | ≥98% |
| Formula | C31H39N7O2 |
| Formula Wt. | 541.69 |
| IUPAC Name | N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-propan-2-ylindazole-4-carboxamide |
| Solubility | Ethanol (2 mg/ml), DMSO (15 mg/ml), DMF (25 mg/ml) |
| Appearance | Light Gray Powder |
Shipping and Storage
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet | |
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References
Amatangelo MD, Garipov A, Li H, et al. Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition. Cell Cycle. 2013 Jul 1;12(13):2113-9. PMID: 23759589.