Description
ALAL is a peptide sequence commonly used as a linker to conjugate compounds together to better target delivery of anticancer chemotherapeutics.
ALAL is a peptide sequence commonly used as a linker to conjugate compounds together to better target delivery of anticancer chemotherapeutics.
| Purity | ≥95% |
|---|---|
| Formula | C18H34N4O5 |
| Formula Wt. | 386.5 |
| Solubility | Soluble in water. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Schmid B, Chung DE, Warnecke A, et al. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy. Bioconjug Chem. 2007 May-Jun;18(3):702-16. PMID: 17378599.
Mier W, Beijer B, Graham K, et al. Fluorescent somatostatin receptor probes for the intraoperative detection of tumor tissue with long-wavelength visible light. Bioorg Med Chem. 2002 Aug;10(8):2543-52. PMID: 12057643.
Fitzpatrick JJ, Garnett MC. Design, synthesis and in vitro testing of methotrexate carrier conjugates linked via oligopeptide spacers. Anticancer Drug Des. 1995 Jan;10(1):1-9. PMID: 7695810.
Bisphosphonate; squalene synthase inhibitor.
Nucleoside (guanosine) analog; DNA chain termin...
Potential p53 activator or SIRT2 inhibitor.
Nitrogen mustard, DNA alkylator.
Aspartyl protease inhibitor.
Mixture of terpene lactones found in Ginkgo.
Triazole; 14-α demethylase and aromatase inhib...
Prostacyclin analog
AMPK activator.
Endogenous peptide hormone; guanyl cyclase C ag...
Macrolide antibiotic; peptidyl transferase inhi...
Found in Schisandra.
Steroid produced by Penicillum; PI3K, mTOR, DNA...
Sesquiterpene lactone derived from Artemesia.
HDAC inhibitor, RNA splicing inhibitor.
Peptide found in insects.
Oltipraz analog, salivary gland secretion enhan...
Tropane alkaloid found in plants in the Solanac...
Mycotoxin metabolite
Promotes degradation of cIAP1