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Altiratinib

Altiratinib

Product ID A4777
Cas No. 1345847-93-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $84.00 In stock
5 mg $162.00 In stock
25 mg $454.00 In stock
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.

Product Info

Cas No.

1345847-93-9

Purity

≥98%

Formula

C26H21F3N4O4

Formula Wt.

510.46

Chemical Name

1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

IUPAC Name

N-[4-({2-[(Cyclopropylcarbonyl)amino]-4-pyridinyl}oxy)-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

Synonym

DCC-2701, DP-5164

Solubility

DMSO: 33mg/mL

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A4777 MSDS PDF

Info Sheet

A4777 Info Sheet PDF

References

Kwon Y, Smith BD, Zhou Y, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53. PMID: 24362531.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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