Description
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Cas No. | 1345847-93-9 |
|---|---|
| Purity | ≥98% |
| Formula | C26H21F3N4O4 |
| Formula Wt. | 510.46 |
| Chemical Name | 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| IUPAC Name | N-[4-({2-[(Cyclopropylcarbonyl)amino]-4-pyridinyl}oxy)-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Synonym | DCC-2701, DP-5164 |
| Solubility | DMSO: 33mg/mL |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Kwon Y, Smith BD, Zhou Y, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53. PMID: 24362531.
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