Description
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Cas No. | 1345847-93-9 |
|---|---|
| Purity | ≥98% |
| Formula | C26H21F3N4O4 |
| Formula Wt. | 510.46 |
| Chemical Name | 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| IUPAC Name | N-[4-({2-[(Cyclopropylcarbonyl)amino]-4-pyridinyl}oxy)-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Synonym | DCC-2701, DP-5164 |
| Solubility | DMSO: 33mg/mL |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Kwon Y, Smith BD, Zhou Y, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53. PMID: 24362531.
Thienylbutyl ITC analog.
Terpene lactone found in Ginkgo; GSK-3β inhibi...
Endogenous peptide, involved in stress signalin...
Degrades of BET proteins.
CB1 agonist, TRPV1 agonist.
Mycotoxin that has structural similarity to est...
Tripeptide, binds cell surface integrins.
Triterpene sapogenin found in species of Panax;...
Phenolic phytoalexin found in soy, grapes, and ...
Sulfonamide; dihydropteroate synthase inhibitor...
Imidazole; 14-α demethylase inhibitor, potenti...
D2/3 agonist.
Camptothecin analog; topoisomerase I inhibitor,...
Triterpene saponin originally found in Bolboste...
Terpene lactone found in Ginkgo.
Diarylether; bacterial ENR binder, fatty acid s...
Folic acid derivative
Neuropeptide found in Locusta migratoria.
Proteasome inhibitor.
p53 activator.