Description
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Cas No. | 1345847-93-9 |
|---|---|
| Purity | ≥98% |
| Formula | C26H21F3N4O4 |
| Formula Wt. | 510.46 |
| Chemical Name | 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| IUPAC Name | N-[4-({2-[(Cyclopropylcarbonyl)amino]-4-pyridinyl}oxy)-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Synonym | DCC-2701, DP-5164 |
| Solubility | DMSO: 33mg/mL |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Kwon Y, Smith BD, Zhou Y, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53. PMID: 24362531.
Peptide fragment of VSV; LDLR agonist.
Allylamine; squalene oxidase and KSR1 inhibitor...
Sesquiterpene lactone found in Ginkgo; GABA-A a...
Diterpene antibiotic produced by Cephalosporum;...
Fatty acid found in dairy products; HDAC inhibi...
JAK1 inhibitor.
Saponin found in Bupleurum, Heteromorpha, and S...
Sulfonamide; dihydropteroate synthase inhibitor...
SIRT2 inhibitor.
Ca2+ ionophore.
Morpholine derivative.
Sesquiterpene lactone derived from Artemesia; m...
Iridoid glycoside found in Gardenia.
Selective 5-HT6 receptor antagonist
CDK1/2 inhibitor.
Aminothiol, CoA component; ulcer inducer.
Lactone found in fungi such as Eupenicillium; g...
Fermentation impurity
Peptide, binds heparin.
(S) isomer of omeprazole; H+/K+ ATPase and MAO-...