Description
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Altiratinib is an inhibitor of c-MET, Tie-2, and VEGFR that exhibits anticancer chemotherapeutic activity. In ovarian cancer models, this compound inhibits cell growth and migration and decreases tumor burden.
| Cas No. | 1345847-93-9 |
|---|---|
| Purity | ≥98% |
| Formula | C26H21F3N4O4 |
| Formula Wt. | 510.46 |
| Chemical Name | 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| IUPAC Name | N-[4-({2-[(Cyclopropylcarbonyl)amino]-4-pyridinyl}oxy)-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Synonym | DCC-2701, DP-5164 |
| Solubility | DMSO: 33mg/mL |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Kwon Y, Smith BD, Zhou Y, et al. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 2015 Jan 8;34(2):144-53. PMID: 24362531.
LRRK2 inhibitor.
RET, EGFR, VEGFR2 inhibitor.
Naturally occuring isothiocyanate found in broc...
Alkaloid found in Stephania.
β1-adrenergic agonist, β2- and α1-adrenergic...
Bumetanide impurity
Natural anthraquinone derivative
5-HT1A partial agonist, SERT inhibitor.
Curcumin derivative.
Synthetic steroid; glucocorticoid agonist.
TRPM8 activator, TRPV3 blocker.
Sulforaphane-cysteine conjugate.
Amphibian tachykinin neuropeptide.
Steroid lactone produced by Withania somnifera;...
Endogenous coenzyme, unit of cellular energy, r...
Echinocandin antifungal
Pleuromutilin
Heterocyclic light-emitting compound, natural l...
Peptide, oxytocin-vasopressin analog.
STING agonist