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Arginine vasopressin peptide (argipressin) is endogenously produced through activation of renin-angiotensin signaling pathways. Argipressin binds vasopressin V1a, V1b, and V2 receptors and exhibits pressor activity, increasing blood pressure. Argipressin induces vasoconstriction, smooth muscle contraction, and retention of water and sodium.
| Cas No. | 113-79-1 |
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| Purity | ≥95% |
| Formula | C46H65N15O12S2 |
| Formula Wt. | 1084.23 |
| IUPAC Name | 1-[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl- 16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14, 17-pentazacycloicosane-4-carbonyl]-N-[1-[(2-amino-2-oxoethyl)amino]-5- (diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide |
| Synonym | Argpressin, 8-Arginine-vasopressin, Pitressin |
| Solubility | Soluble in water (0.5 mg/mL). |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Cao T, Feng Y. The (pro)renin receptor and body fluid homeostasis. Am J Physiol Regul Integr Comp Physiol. 2013 Jul 15;305(2):R104-6. PMID: 23678024.
Palazzuoli A, Ronco C. Cardio-renal syndrome: an entity cardiologists and nephrologists should be dealing with collegially. Heart Fail Rev. 2011 Nov;16(6):503-8. PMID: 21822604.
Ryckmans T. Modulation of the vasopressin system for the treatment of CNS diseases. Curr Opin Drug Discov Devel. 2010 Sep;13(5):538-47. PMID: 20812145.