• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
AS-604850

AS-604850

Product ID A7202
Cas No. 648449-76-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $63.60 In stock
5 mg $209.60 In stock
10 mg $364.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AS-604850 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory and immunosuppressive activities. In animal models of experimental autoimmune encephalitis (EAE), AS-604850 decreases the number of leukocytes infiltrated into the CNS and ameliorates disease symptoms. AS-604850 also decreases chemotactic responses of eosinophils to platelet activating factor (PAF).

Product Info

Cas No.

648449-76-7

Purity

≥98%

Formula

C11H5F2NO4S

Formula Wt.

285.22

IUPAC Name

(5E)-5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

Synonym

AS604850

Solubility

DMSO 57 mg/mL (199.84 mM) Ethanol 5 mg/mL (17.53 mM) Water Insoluble

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A7202 MSDS PDF

Info Sheet

A7202 Info Sheet PDF

References

Li H, Park D, Abdul-Muneer PM, et al. PI3Kγ inhibition alleviates symptoms and increases axon number in experimental autoimmune encephalomyelitis mice. Neuroscience. 2013 Dec 3;253:89-99. PMID: 24012746.

Hasan AM, Mourtada-Maarabouni M, Hameed MS, et al. Phosphoinositide 3-kinase gamma mediates chemotactic responses of human eosinophils to platelet-activating factor. Int Immunopharmacol. 2010 Sep;10(9):1017-21. PMID: 20685403.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H9726

    Hygromycin B

    Protein translocation inhibitor.

    ≥95.0%
  • F5874

    Fosfomycin Calcium

    MurA and isopentenyl mevalonate kinase inhibito...

    ≥95%
  • L1628

    Ac-LEHD-pNa

    Caspase 9 substrate.

    ≥95%
  • W7201

    WS6

    Islet α/β cell proliferation stimulator.

    ≥98%
  • G346851

    Givinostat Hydrochloride

    Non-selective HDAC inhibitor.

    ≥98%
  • F3473

    Fisetin

    Flavonoid found in various plant sources; matri...

    ≥97%
  • G681019

    Grapiprant

    EP4 receptor antagonist

    ≥98%
  • C0155

    10-Hydroxycamptothecin

    Camptothecin derivative; topoisomerase I inhibi...

    ≥98%
  • H1662

    HER2/neu (654-662) GP2

    Peptide fragment of HER2/neu/erbB2 receptor.

    ≥95%
  • A600002

    AP-26113

    Pan inhibitor of ALK.

    ≥98%
  • P0219

    Paeonol

    Found in Paeonia, Arisaema, Dioscorea; MAO-A/B ...

    ≥98%
  • M2077

    1-Methoxy-5-methylphenazinium Methyl Sulfate

    Electron carrier used to study dehydrogenase el...

    ≥98%
  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • T9968

    Tyrphostin A25

    SK K+ channel blocker, EGFR inhibitor.

    ≥98%
  • D1859

    2-Deoxy-D-glucose

    Glucose metabolism inhibitor, N-linked glycosyl...

    ≥99%
  • S7603

    Stavudine

    Nucleoside (thymidine) analog; DNA chain termin...

    ≥99%
  • A1017

    Aceclofenac

    Diclofenac analog, NSAID; COX-2 inhibitor.

    ≥98%
  • C9808

    CZC-54252

    LRRK2 inhibitor.

    ≥98%
  • C0266

    Capsaicin, natural

    Found in Capsicum; TRPV agonist.

    ≥95%, capsaicinoids content
  • S1059

    Scopolamine Hydrobromide Trihydrate

    Tropane alkaloid found in Solanaceae plants; M1...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only