• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
AS-604850

AS-604850

Product ID A7202
Cas No. 648449-76-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $63.60 In stock
5 mg $209.60 In stock
10 mg $364.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AS-604850 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory and immunosuppressive activities. In animal models of experimental autoimmune encephalitis (EAE), AS-604850 decreases the number of leukocytes infiltrated into the CNS and ameliorates disease symptoms. AS-604850 also decreases chemotactic responses of eosinophils to platelet activating factor (PAF).

Product Info

Cas No.

648449-76-7

Purity

≥98%

Formula

C11H5F2NO4S

Formula Wt.

285.22

IUPAC Name

(5E)-5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

Synonym

AS604850

Solubility

DMSO 57 mg/mL (199.84 mM) Ethanol 5 mg/mL (17.53 mM) Water Insoluble

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A7202 MSDS PDF

Info Sheet

A7202 Info Sheet PDF

References

Li H, Park D, Abdul-Muneer PM, et al. PI3Kγ inhibition alleviates symptoms and increases axon number in experimental autoimmune encephalomyelitis mice. Neuroscience. 2013 Dec 3;253:89-99. PMID: 24012746.

Hasan AM, Mourtada-Maarabouni M, Hameed MS, et al. Phosphoinositide 3-kinase gamma mediates chemotactic responses of human eosinophils to platelet-activating factor. Int Immunopharmacol. 2010 Sep;10(9):1017-21. PMID: 20685403.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T174441

    Telacebec

    Anti-tuberculosis

    ≥98%
  • I4962

    Isoimperatorin

    Furocoumarin; COX-2 inhibitor.

    ≥98%
  • P2994

    Physalaemin

    Amphibian tachykinin neuropeptide.

    ≥95%
  • A480020

    (R,S)-AM 1241

    Cannabinoid receptor 2 selective agonist.

    ≥96%
  • G1651

    Geniposidic Acid

    Iridoid glucoside found in Eucommia, Castilleja...

    ≥98%
  • R2353

    RF-NH2

    RF-amide peptide; potential GPR147 agonist, pot...

    ≥95%
  • P4780

    Plumbagin

    Naphthoquinone found in Plumbago.

    ≥98%
  • C9882

    Cytochalasin E

    Mycotoxin produced by Aspergillus; actin polyme...

    ≥98%
  • M9645

    Myelin Oligodendrocyte Glycoprotein (35-55), rat

    Oligodendrocyte antigen used to induce EAE.

    ≥95%
  • B3458

    Biopterin

    Endogenous pterin coenzyme required for release...

    ≥98%
  • Z160021

    Zearalanone

    Mycotoxin.

    ≥97%
  • E5210

    Endomorphin-1

    Endogenous opioid peptide; μOr agonist.

    ≥95%
  • C8502

    CV-70

    1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...

    ≥70%
  • M0248

    Manidipine Dihydrochloride

    Dihydropyridine; L-type and T-type Ca2+ channel...

    ≥99%
  • M5853

    Moniliformin sodium salt

    Mycotoxin produced by species of Fusarium; pote...

    ≥98%
  • H9613

    N-(4-Hydroxyphenyl)retinamide

    Retinol (vitamin A) analog, binds RBP4; Des1 in...

    ≥98%
  • K0032

    Kahweol Palmitate

    Diterpene found in coffee beans.

    ≥97%
  • E5477

    Entinostat

    Benzamide; HDAC1 inhibitor.

    ≥98%
  • C1867

    Ceramide

    Endogenous sphingosine-based lipid, component of s...
    ≥98%
  • B7973

    Busulfan

    Alkyl sulfonate; DNA alkylator.  
    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only