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AS-604850

AS-604850

Product ID A7202
Cas No. 648449-76-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $63.60 In stock
5 mg $209.60 In stock
10 mg $364.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AS-604850 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory and immunosuppressive activities. In animal models of experimental autoimmune encephalitis (EAE), AS-604850 decreases the number of leukocytes infiltrated into the CNS and ameliorates disease symptoms. AS-604850 also decreases chemotactic responses of eosinophils to platelet activating factor (PAF).

Product Info

Cas No.

648449-76-7

Purity

≥98%

Formula

C11H5F2NO4S

Formula Wt.

285.22

IUPAC Name

(5E)-5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

Synonym

AS604850

Solubility

DMSO 57 mg/mL (199.84 mM) Ethanol 5 mg/mL (17.53 mM) Water Insoluble

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A7202 MSDS PDF

Info Sheet

A7202 Info Sheet PDF

References

Li H, Park D, Abdul-Muneer PM, et al. PI3Kγ inhibition alleviates symptoms and increases axon number in experimental autoimmune encephalomyelitis mice. Neuroscience. 2013 Dec 3;253:89-99. PMID: 24012746.

Hasan AM, Mourtada-Maarabouni M, Hameed MS, et al. Phosphoinositide 3-kinase gamma mediates chemotactic responses of human eosinophils to platelet-activating factor. Int Immunopharmacol. 2010 Sep;10(9):1017-21. PMID: 20685403.

Custom Order

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