• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
9-Aminocamptothecin Hydrochloride

9-Aminocamptothecin Hydrochloride

Product ID A491337
Cas No. 91421-43-1 (free base)
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $71.50 In stock
10 mg $321.00 In stock
25 mg $668.40 In stock
50 mg $1,113.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

9-amino-Camptothecin is a camptothecin derivative. Camptothecin is a quinolone alkaloid precursor of irinotecan; it is originally found in Camptotheca. Camptothecin exhibits anticancer chemotherapeutic activity, inhibiting topoisomerase I and inducing double-stranded DNA breaks. Camptothecin is extremely cytotoxic and only its derivatives are clinically used as chemotherapeutics.

Product Info

Cas No.

91421-43-1 (free base)

Purity

≥98%

Formula

C20H17N3O4 • HCl

Formula Wt.

399.83

Synonym

9-Amino-20-camptothecin HCl; 9-AC HCl

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A491337 MSDS PDF

Info Sheet

A491337 Info Sheet PDF

References

Rodríguez-Berna G, Mangas-Sanjuán V, Gonzalez-Alvarez M, et al. A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability. Eur J Med Chem. 2014 Jun 25;83C:366-373. PMID: 24980118.

Berniak K, Rybak P, Bernas T, et al. Relationship between DNA damage response, initiated by camptothecin or oxidative stress, and DNA replication, analyzed by quantitative 3D image analysis. Cytometry A. 2013 Jul 11. [Epub ahead of print]. PMID: 23846844.

Redinbo MR, Stewart L, Kuhn P, et al. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998 Mar 6;279(5356):1504-13. PMID: 9488644.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • O486179

    Omeprazole Impurity C

    Impurity of omeprazole

    ≥99%
  • R0249

    Ramipril

    ACE inhibitor.

    ≥98%
  • J974440

    JZL184

    MAGL inhibitor.

    ≥98%
  • E5575

    Entacapone

    COMT inhibitor.

    ≥98%
  • G1658

    Gentamycin Sulfate

    Aminoglycoside; protein translation inhibitor.<...

  • D5792

    Doxofylline

    Xanthine derivative; PDE inhibitor.

    ≥98%
  • M1605

    Mebendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • G2869

    Ghrelin, rat

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • G7345

    GSK-2606414

    PERK inhibitor.

    ≥99%
  • E6134

    Epimedin C

    Flavonoid found in Epimedium sagittatum.

    ≥98%
  • R6052

    Recombinant Mycoplasma Pneumonia Antigen

    Pneumonia antigen

  • P3597

    Pizotyline Malate

    5-HT1A partial agonist, 5-HT2C antagonist.

    ≥98%
  • M0114

    Madecassic Acid

    Downregulates LPS-stimulated expression of pro-...

    ≥95%
  • G7200

    GS-967

    Na+ channel blocker.

    ≥98%
  • I458579

    Iloprost

    Prostacyclin analog

    ≥98%
  • B1973

    Besifloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • I7468

    Isradipine

    Calcium channel blocker.

    ≥98%
  • B5870

    Borrelidin

    Macrolide; threonyl-tRNA synthetase/ligase inhi...

    ≥99%
  • C167200

    Cefazolin

    Cephalosporin analogue

    ≥98%
  • A5056

    Amorolfine Hydrochloride

    14α-demethylase inhibitor.

    ≥98.5%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only