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AZD-6482

AZD-6482

Product ID A9712
Cas No. 1173900-33-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $110.40 In stock
5 mg $240.10 In stock
10 mg $415.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AZD-6482 is an inhibitor of p110β PI3K. AZD-6482 inhibits insulin-induced adipocyte glucose uptake in vitro and increases glucose homeostasis in vivo. Additionally, AZD-6482 exhibits antithrombotic activity without increasing bleeding time or blood loss in other animal models.

Product Info

Cas No.

1173900-33-8

Purity

≥98%

Formula

C22H24N4O4

Formula Wt.

408.45

IUPAC Name

2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid

Solubility

DMSO 82 mg/mL (200.75 mM) Ethanol 10 mg/mL (24.48 mM) Water Insoluble

Appearance

Off-white Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A9712 MSDS PDF

Info Sheet

A9712 Info Sheet PDF

References

Weigelt B, Warne PH, Lambros MB, et al. PI3K pathway dependencies in endometrioid endometrial cancer cell lines. Clin Cancer Res. 2013 Jul 1;19(13):3533-44. PMID: 23674493.

Nylander S, Kull B, Björkman JA, et al. Human target validation of phosphoinositide 3-kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor. J Thromb Haemost. 2012 Oct;10(10):2127-36. PMID: 22906130.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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