Description
B-Raf IN 1 inhibits both B-Raf and c-Raf, likely displaying anticancer activity.
Product Unit Size | Cost | Quantity | Stock |
---|
B-Raf IN 1 inhibits both B-Raf and c-Raf, likely displaying anticancer activity.
Cas No. | 950736-05-7 |
---|---|
Purity | ≥98% |
Formula | C29H24F3N5O |
Formula Wt. | 515.54 |
IUPAC Name | N-[3-(3-{4-[(Dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide |
Solubility | DMSO: ≥ 53 mg/mL |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet | |
Brochures |
Berger DM, Torres N, Dutia M, et al. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. PMID: 19864136.
R-type Ca2+ and voltage-gated Na+ channel block...
Phenylpyrazoleanilide; IL-17 production inhibit...
Fungistatic
Terpene lactone found in Ginkgo; GSK-3β inhibi...
Mouse selective STING agonist.
Staurosporine analog; PKC and PKA inhibitor.
Polyphenolic compound present in black tea.
Fluoroquinolone; topoisomerase IV, topoisomeras...
H+/K+ ATPase and ROCK-2 inhibitor.
Mycotoxin produced by Aspergillus; actin polyme...
Endogenous opioid peptide; δOR and μOR agonis...
Endogenous peptide, cleavage product of angiote...
Chaetocin is naturally produced by Chaetomium s...
HSP90 inhibitor.
SIRT1/2 inhibitor, indirect p53 activator.
Endogenous neurotransmitter; GABA agonist.
Sesquiterpene lactone found in Saussurea.
Steroid; glucocorticoid agonist.
Non-endogenous essential amino acid found in me...
Low osmolarity contrast agent used for imaging ...