Description
B-Raf IN 1 inhibits both B-Raf and c-Raf, likely displaying anticancer activity.
| Product Unit Size | Cost | Quantity | Stock |
|---|
B-Raf IN 1 inhibits both B-Raf and c-Raf, likely displaying anticancer activity.
| Cas No. | 950736-05-7 |
|---|---|
| Purity | ≥98% |
| Formula | C29H24F3N5O |
| Formula Wt. | 515.54 |
| IUPAC Name | N-[3-(3-{4-[(Dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide |
| Solubility | DMSO: ≥ 53 mg/mL |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Berger DM, Torres N, Dutia M, et al. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. PMID: 19864136.
Negative control for PKC activation.
Peptide, vSrc-induced cytokine.
Lignan found in Magnolia; GABA-A potentiator.
Laminin-derived peptapeptide.
Fluorinated aminopropyl carbazole, neuroprotect...
Non-proteinogenic amino acid, L-arginine metabo...
Glutamine analog; γ-glutamyl transferase, CTP ...
Dithiolopyrrolone; RNA polymerase inhibitor.
Non-fluorescent halogenated A23187 analog, Ca2+...
STING agonist
Snake venom found in Crotalus durrisus terrific...
Cell-penetrating peptide, carries large conjuga...
Antimicrobial peptide found in Apis mellifera.<...
Diterpene vitamin A; RAR/RXR agonist.
Ras inhibitor.
NSAID; COX-2 inhibitor.
BH3 mimetic; Bcl-2, Bxl-xl, Bcl-w inhibitor.
Flavonoid originally found in Silybum (milk thi...
Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...
Folate analog; thymidylate synthase inhibitor.<...