Description
Lupinine is a plant alkaloid found in species of Loranthus, Calia, and Lupinus. Lupinine exhibits immunostimulatory activity, potentially through the activation of CD69. Lupinine inhibits cholinesterases and may also inhibit heparin.
Lupinine is a plant alkaloid found in species of Loranthus, Calia, and Lupinus. Lupinine exhibits immunostimulatory activity, potentially through the activation of CD69. Lupinine inhibits cholinesterases and may also inhibit heparin.
Cas No. | 486-70-4 |
---|---|
Purity | ≥98% |
Formula | C10H19NO |
Formula Wt. | 169.26 |
Chemical Name | [1R-trans]-Octahydro-2H-quinolizine-1-methanol |
IUPAC Name | [(1R,9aR)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-yl]methanol |
Synonym | l-Lupine, (-)-Lupinine |
Melting Point | 68.5-69.2°C |
Solubility | Soluble in water, alcohol, chloroform and ether. |
Appearance | Light brown orange crystalline powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Basova NE, Kormilitsyn BN, Perchenok AIu, et al. Reversible lupininin inhibitors of cholinesterases of mammalian blood and of optical ganglia of individuals of the commander squid Berryteuthis magister from different zones of species areal. Zh Evol Biokhim Fiziol. 2012 May-Jun;48(3):213-8. PMID: 22827020.
Omeje EO, Osadebe PO, Nworu CS, et al. A novel sesquiterpene acid and an alkaloid from leaves of the Eastern Nigeria mistletoe, Loranthus micranthus with potent immunostimulatory activity on C57BL6 mice splenocytes and CD69 molecule. Pharm Biol. 2011 Dec;49(12):1271-6. PMID: 21988279.
Usmanova DM, Musaev UN, Efimov VS. Antiheparin activity of polymers based on the alkaloid, lupinine. Farmakol Toksikol. 1979 Nov-Dec;42(6):628-32. PMID: 499471.
Triterpene saponin found in Panax; Kv7.1 K+ cha...
EGFR and PDGFR inhibitor
Fluoroquinolone; bacterial DNA gyrase inhibitor...
HDAC1/2/3/11 inhibitor.
Pt-based DNA cross-linker.
Sesquiterpene lactone found in Thapsia, used to...
beta-catenin inhibitor
Endogenous opioid peptide; μOR agonist.
Anthracycline, DNA intercalator; topoisomerase ...
Wee1 inhibitor.
Coumarin; VKORC1 inhibitor.
Amino acid alcohol.
Anthraquinone pigment found in madder root; O-a...
Orexin 2 receptor antagonist
α1-adrenergic agonist.
Triazole; 14-α demethylase inhibitor, potentia...
Aminocyclitol; protein synthesis inhibitor.
Triterpenoid found in Centella.
Synthetic vitamin E, antioxidant.
COMT inhibitor.