Description
This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
| Product Unit Size | Cost | Quantity | Stock |
|---|
This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
| Cas No. | 173101-56-9 |
|---|---|
| Purity | ≥95% |
| Formula | C48H53NO14 |
| Formula Wt. | 867.93 |
| IUPAC Name | [4,12-diacetyloxy-1,9-dihydroxy-15-[2-hydroxy-3-phenyl-3-[(2-phenylacetyl)amino]propanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Synonym | Taxol F; Paclitaxel impurity P; |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.
Orr GA, Verdier-Pinard P, McDaid H, et al. Mechanisms of Taxol resistance related to microtubules. Oncogene. 2003 Oct 20;22(47):7280-95. PMID: 14576838.
Jordan MA. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem Anticancer Agents. 2002 Jan;2(1):1-17. PMID: 12678749.
Taxoid that disrupts the microtubular network i...
FIASMA, σ1, RyR2, TrkA/B agonist; SERT, NET in...
Benzamide; HDAC1 inhibitor.
MEK inhibitor.
Cell-membrane permeable heterocyclic light-emit...
Chaetocin is naturally produced by Chaetomium s...
Synthetic catechol; ER agonist, microtubule pol...
JAK2 inhibitor.
Thiazide-like diuretic; Kv7.1 and minK K+ chann...
FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...
Synthetic steroid hormone; AR agonist, ER and P...
Tetracycline; FIASMA, histamine H1, 5-HT2, mACh...
Thienylbutyl ITC analog.
Xanthine alkaloid found in coffee, tea, and oth...
Peptide, neurotensin analog.
Sesquiterpene alkaloid found in Huperzia serrat...
Peptidyl transferase inhibitor, protein transla...
NS3/4A serine protease inhibitor.
EGFR (WT, T790M) inhibitor.
Monoterpene; nAChR antagonist.