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Boceprevir

Product ID B564086
Cas No. 394730-60-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $117.70 In stock
25 mg $323.70 In stock
100 mg $1,147.80 In stock
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  • Product Info
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  • References
  • Description
  • Product Info
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  • Downloads
  • References
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Description

Boceprevir is an antiviral bioactive small molecule. Found to inhibit Mpro activity and SARS-CoV-2 in Vero cells.

Product Info

Cas No.

394730-60-0

Purity

≥98%

Formula

C27H45N5O5

Formula Wt.

519.69

Chemical Name

(1R,2S,5S)-N-(4-amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

IUPAC Name

(1R,2S,5S)-N-(4-amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

Synonym

Victrelis, SCH 503034, EBP 520

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

References

Fu L, Ye F, Feng Y, et al. Both boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun. 2020 Sep 4;11(1):4417. PMID: 32887884.

Oerlemans R, Ruiz-Moreno A, Cong Y, et al. Repurposing the HCV NS3-4A protease drug boceprevir as COVID-19 therapeutics. RSC Med Chem. 2021 Mar 1;12(3):370-379. PMID: 34041486.

Ma C, Sacco M, Hurst B, et al. Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease. Cell Res. 2020 Aug;30(8):678-692. PMID: 32541865.

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