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Butoconazole Nitrate

Product ID B8278
Cas No. 64872-77-1
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $68.30 In stock
250 mg $109.40 In stock
1 g $342.60 In stock
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  • Description
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Description

Butoconazole is an imidazole derivative that exhibits antifungal/antimycotic and anti-parasitic activities; it likely inhibits 14-α demethylase. Butoconazole displays particularly effective antimicrobial activity against species of Candida, Saccharomyces, and Trichomonas.

Product Info

Cas No.

64872-77-1

Purity

≥98%

Formula

C19H17Cl3N2S • HNO3

Formula Wt.

474.79

Chemical Name

1-[4-(4-chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole;nitric acid

IUPAC Name

1-[4-(4-chlorophenyl)-2-(2, 6-dichlorophenyl)sulfanylbutyl]imidazole;nitric acid

Synonym

Femstat, Gynomyk, Gynazole-1

Melting Point

159°C (dec.)

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

B8278 MSDS PDF

Info Sheet

B8278 Info Sheet PDF

References

Seidman LS, Skokos CK. An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis. Infect Dis Obstet Gynecol. 2005 Dec;13(4):197-206. PMID: 16338779.

Bourée P, Issoire C. In vitro evaluation of the activity of butoconazole against Trichomonas vaginalis. Pathol Biol (Paris). 1992 May;40(5):492-4. PMID: 1495832.

Hernández Molina JM, Llosá J, Martinez Brocal A, et al. In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp. Mycopathologia. 1992 Apr;118(1):15-21. PMID: 1406898.

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