• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Brivudine

Brivudine

Product ID B6935
Cas No. 69304-47-8
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $210.00 In stock
25 mg $399.00 In stock
100 mg $1,039.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Brivudine is a L-nucleoside analog of thymidine that exhibits antiviral, anticancer chemotherapeutic, and insecticidal activities. Brivudine inhibits herpes simplex virus (HSV-1) thymidine kinase, preventing DNA chain elongation and inhibiting viral growth. Brivudine also binds heat shock protein 27 (HSP27/HSPB1), improving the efficacy of co-administered chemotherapeutics in vivo and in clinical settings. This compound also exhibits properties of an insecticide, slowing larval growth and development of Spodoptera worms.

Product Info

Cas No.

69304-47-8

Purity

≥98%

Formula

C11H13BrN2O5

Formula Wt.

333.13

Chemical Name

5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC Name

5-[(E)-2-bromoethenyl]-1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Melting Point

165°C

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

B6935 MSDS PDF

Info Sheet

B6935 Info Sheet PDF

References

Heinrich JC, Tuukkanen A, Schroeder M, et al. RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients. J Cancer Res Clin Oncol. 2011 Sep;137(9):1349-61. PMID: 21833720.

Breuer M, De Loof A, Balzarini J, et al. Insecticidal activity of the pyrimidine nucleoside analogue (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU). Pest Manag Sci. 2005 Aug;61(8):737-41. PMID: 15838935.

Spadari S, Ciarrocchi G, Focher F, et al. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies. Mol Pharmacol. 1995 Jun;47(6):1231-8. PMID: 7603465.

Balzarini J, Bohman C, De Clercq E. Differential mechanism of cytostatic effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, and other antiherpetic drugs on tumor cells transfected by the thymidine kinase gene of herpes simplex virus type 1 or type 2. J Biol Chem. 1993 Mar 25;268(9):6332-7. PMID: 8384209.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B1979

    Betulinic Acid

    Pentacyclic triterpene.

    ≥99%
  • D1720

    Deferiprone

    Iron chelator.

    ≥99%
  • C1844

    Celastrol

    Triterpene isolated Trypterigium wilfordii; HSP...

    ≥98%
  • P6959

    Prothionamide

    Nicotinic acid derivative; InhA inhibitor.

    ≥98%
  • A5281

    Angiotensin II (4-8), human

    Endogenous peptide fragment, involved in vasoco...

    ≥95%
  • L8377

    Luteolin

    Flavonoid found in various plant sources; DAT a...

    ≥95%
  • B1640

    Benzydamine Hydrochloride

    NSAID; PG synthetase inhibitor.

    ≥98%
  • B8278

    Butoconazole Nitrate

    Imidazole; 14-α demethylase inhibitor.

    ≥98%
  • P7034

    Prion Peptide (106-126), human

    Synthetic peptide fragment, prion protein analo...

    ≥95%
  • A5161

    Ampiroxicam

    Piroxicam prodrug, NSAID; COX-1/2 inhibitor.

    ≥98%
  • A4547

    Alloxan Monohydrate

    Pyrimidine, glucose analog, used to induce diab...

    ≥98%
  • R3347

    Riluzole

    Benzothiazole; TRPC5 agonist, PTR1 inhibitor, v...

    ≥98%
  • R5874

    Rosmarinic Acid

    Caffeic acid ester found in Melissa, Salvia, an...

    ≥98%
  • S8013

    [Tyr8]-Substance P

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • R0348

    Ramelteon

    Melatonin analog; MT1/2 agonist.

    ≥99%
  • T3132

    Thiazovivin

    ROCK inhibitor.

    ≥98%
  • A4440

    Allicin

    Organosulfur found in garlic, binds DNA; inward...

    ≥98%
  • N0123

    Naftopidil

    α1-adrenergic antagonist.

    ≥98%
  • D3462

    Diphenhydramine Hydrochloride

    Voltage-gated Na+ channel blocker, mAChR antago...

    ≥98%
  • R0245

    Raltitrexed

    Folate analog; thymidylate synthase inhibitor.<...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only