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Buspirone Hydrochloride

Product ID B8274
Cas No. 33386-08-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $94.40 In stock
5 g $314.90 In stock
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  • Product Info
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  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
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Description

Buspirone is an azapirone anxiolytic that acts as a partial agonist at 5-HT1A receptors and α1-adrenergic receptors and an antagonist at D2/3/4 receptors. Buspirone is clinically used to treat anxiety. In animal models, buspirone inhibits MMPP-induced enhancements in memory acquisition and formation.

Product Info

Cas No.

33386-08-2

Purity

≥98%

Formula

C21H31N5O2 • HCl

Formula Wt.

421.97

Chemical Name

8-[4-[4-(2-Pyrimidinyl)=1=piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride

IUPAC Name

8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7, 9-dione;hydrochloride

Synonym

Anisal, Axoren, Bespar, Buspinol, Narol

Melting Point

201.5-202.5°C

Solubility

Soluble in water.

Appearance

White powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

B8274 MSDS PDF

Info Sheet

B8274 Info Sheet PDF

References

Navarrete A, Flores-Machorro FX, Téllez-Ballesteros RI, et al. Study on action mechanism of 1-(4-methoxy-2-methylphenyl)piperazine (MMPP) in acquisition, formation, and consolidation of memory in mice. Drug Dev Res. 2014 Mar;75(2):59-67. PMID: 24648132.

Loane C, Politis M. Buspirone: what is it all about? Brain Res. 2012 Jun 21;1461:111-8. PMID: 22608068.

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