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Carmustine

Carmustine

Product ID C0173
Cas No. 154-93-8
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $75.10 In stock
100 mg $285.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Carmustine is a nitrosourea alkylator that is clinically used to treat brain cancers, multiple myeloma, and lymphomas. Carmustine exhibits anticancer chemotherapeutic and anticoagulant activities. Carmustine is often co-administered with MGMT inhibitors to increase its chemotherapeutic efficacy. In vitro and in vivo, carmustine also induces apoptosis in platelets, increasing bleeding time.

Product Info

Cas No.

154-93-8

Purity

≥98%

Formula

C5H9Cl2N3O2

Formula Wt.

214.05

Chemical Name

N,N'-Bis(2-chloroethyl)-N-nitrosourea

IUPAC Name

1,3-bis(2-chloroethyl)-1-nitrosourea

Synonym

Becenun, Bicnu, Carmubris

Melting Point

30-32°C

Solubility

Soluble in water (4 mg/mL), 50% ethanol (150 mg/mL), DMSO.

Appearance

Yellowish Crystal

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C0173 MSDS PDF

Info Sheet

C0173 Info Sheet PDF

References

Zhang J, Chen M, Zhang Y, et al. Carmustine induces platelet apoptosis. Platelets. 2014 Jun 23:1-6. [Epub ahead of print]. PMID: 24955606.

Drabløs F, Feyzi E, Aas PA, et al. Alkylation damage in DNA and RNA--repair mechanisms and medical significance. DNA Repair (Amst). 2004 Nov 2;3(11):1389-407. PMID: 15380096.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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