• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register

Caspofungin Diacetate

Product ID C0274
Cas No. 179463-17-3
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $92.80 In stock
25 mg $340.70 In stock
100 mg $1,063.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Caspofungin acetate is a lipopeptide antifungal that inhibits the enzyme 1,3-β-Glucan synthase, which synthesizes β-glucan polymers that form fungal cell walls. Caspofungin acetate is active against a variety of Aspergillus and Candida species and unlike many antifungals, is not metabolized by the cytochrome p450 system. The ability of caspofungin acetate to inhibit β-glucan synthesis decreases cell wall mechanical strength, alters cell surface hydrophobicity, and triggers cell aggregation.

Product Info

Cas No.

179463-17-3

Purity

≥95%

Formula

C52H88N10O15 • C4H8O4

Formula Wt.

1213.42

Synonym

Caspofungin Acetate, MK-0991

Melting Point

204-206°C

Solubility

Soluble in ethanol (20 mg/mL), DMSO (25 mg/mL), DMF (20 mg/mL), water (10 mg/mL), methanol.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C0274 MSDS PDF

Info Sheet

C0274 Info Sheet PDF

References

El-Kirat-Chatel S, Beaussart A, Alsteens D, et al. Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans. Nanoscale. 2013 Feb 7;5(3):1105-15. PMID: 23262781.

Pacetti SA, Gelone SP. Caspofungin acetate for treatment of invasive fungal infections. Ann Pharmacother. 2003 Jan;37(1):90-8. PMID: 12503942.

Mio T, Adachi-Shimizu M, Tachibana Y, et al. Cloning of the Candida albicans homolog of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in beta-1,3-glucan synthesis. J Bacteriol. 1997 Jul;179(13):4096-105. PMID: 9209021.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2023 LKT Laboratories, All Rights Reserved - Products for research use only