Description
CCCP inhibits mitochondrial oxidative phosphorylation.
CCCP inhibits mitochondrial oxidative phosphorylation.
| Cas No. | 555-60-2 |
|---|---|
| Purity | ≥99% |
| Formula | C9H5ClN4 |
| Formula Wt. | 204.62 |
| IUPAC Name | 2-[(3-chlorophenyl)hydrazinylidene]propanedinitrile |
| Synonym | Carbonyl cyanide m-chlorophenyl hydrazone; Carbonyl cyanide 3-chlorophenylhydrazone; m-Cl-CCP; Mesoxalonitrile 3-chlorophenylhydrazone |
| Appearance | Brown powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sanchez-Carbonel A, Mondragon B, Lopez-Chegne N, et al. The effect of the efflux pump inhibitor carbonyl cyanide m-chlorophenylhydrazone (CCCP) on the susceptibility to imipenem and cefepime in clinical strains of Acinetobacter baumannii. PLoS One. 2021 Dec 17;16(12):e0259915. PMID: 34919563
Koncha R, Ramachandran G, Sepuri N, et al. CCCP-induced mitochondrial dysfunction - characterization and analysis of integrated stress response to cellular signaling and homeostasis. FEBS J. 2021 Oct;288(19):5737-5754. PMID: 33837631
Chen S, Teng T, Zhang Z, et al. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) exhibits direct antibacterial activity against Mycobacterium abscessus. Infect Drug Resist. 2021 Mar 23;14:1199-1208. PMID: 33790590
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