Description
CCCP inhibits mitochondrial oxidative phosphorylation.
CCCP inhibits mitochondrial oxidative phosphorylation.
| Cas No. | 555-60-2 |
|---|---|
| Purity | ≥99% |
| Formula | C9H5ClN4 |
| Formula Wt. | 204.62 |
| IUPAC Name | 2-[(3-chlorophenyl)hydrazinylidene]propanedinitrile |
| Synonym | Carbonyl cyanide m-chlorophenyl hydrazone; Carbonyl cyanide 3-chlorophenylhydrazone; m-Cl-CCP; Mesoxalonitrile 3-chlorophenylhydrazone |
| Appearance | Brown powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sanchez-Carbonel A, Mondragon B, Lopez-Chegne N, et al. The effect of the efflux pump inhibitor carbonyl cyanide m-chlorophenylhydrazone (CCCP) on the susceptibility to imipenem and cefepime in clinical strains of Acinetobacter baumannii. PLoS One. 2021 Dec 17;16(12):e0259915. PMID: 34919563
Koncha R, Ramachandran G, Sepuri N, et al. CCCP-induced mitochondrial dysfunction - characterization and analysis of integrated stress response to cellular signaling and homeostasis. FEBS J. 2021 Oct;288(19):5737-5754. PMID: 33837631
Chen S, Teng T, Zhang Z, et al. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) exhibits direct antibacterial activity against Mycobacterium abscessus. Infect Drug Resist. 2021 Mar 23;14:1199-1208. PMID: 33790590
Mycotoxin, metabolite of aflatoxin B1 produced ...
SIRT1/2 inhibitor, indirect p53 activator.
Mas antagonist.
SGLT2 inhibitor
Endogenous opioid peptide; δOR and μOR agonis...
Amino acid precursor of dopamine.
Mycotoxin that has structural similarity to est...
Fluoroquinolone; bacterial DNA gyrase inhibitor...
Peptide, IgG derivative, tuftsin analog.
Furanocoumarin found in Psoralea coryfolia, DNA...
MET, VEGFR2, Ron, Axl, FLT3 inhibitor.
TrkB agonist.
Nucleoside (guanosine) analog; RT, guanylyl cyc...
Phenol found in Zingiber; 5-HT3 antagonist.
AMPK activator, D1-4, 5-HT1A/2/3/6/7, M1-5 mACh...
Fibrate; PPARα agonist.
BTK inhibitor.
Mycotoxin that has structural similarity to est...
B-Raf and c-Raf inhibitor.
Diterpene compound originally found in Rosmarin...