Description
CCCP inhibits mitochondrial oxidative phosphorylation.
CCCP inhibits mitochondrial oxidative phosphorylation.
| Cas No. | 555-60-2 |
|---|---|
| Purity | ≥99% |
| Formula | C9H5ClN4 |
| Formula Wt. | 204.62 |
| IUPAC Name | 2-[(3-chlorophenyl)hydrazinylidene]propanedinitrile |
| Synonym | Carbonyl cyanide m-chlorophenyl hydrazone; Carbonyl cyanide 3-chlorophenylhydrazone; m-Cl-CCP; Mesoxalonitrile 3-chlorophenylhydrazone |
| Appearance | Brown powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sanchez-Carbonel A, Mondragon B, Lopez-Chegne N, et al. The effect of the efflux pump inhibitor carbonyl cyanide m-chlorophenylhydrazone (CCCP) on the susceptibility to imipenem and cefepime in clinical strains of Acinetobacter baumannii. PLoS One. 2021 Dec 17;16(12):e0259915. PMID: 34919563
Koncha R, Ramachandran G, Sepuri N, et al. CCCP-induced mitochondrial dysfunction - characterization and analysis of integrated stress response to cellular signaling and homeostasis. FEBS J. 2021 Oct;288(19):5737-5754. PMID: 33837631
Chen S, Teng T, Zhang Z, et al. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) exhibits direct antibacterial activity against Mycobacterium abscessus. Infect Drug Resist. 2021 Mar 23;14:1199-1208. PMID: 33790590
Synthesis impurity
Tetracycline; protein translation inhibitor, MM...
KRAS inhibitor
BRD2/3/4 inhibitor.
Glycosaminoglycan
Cephalotaxine alkaloid originally found in Ceph...
Endogenous peptide, involved in water/Na+ homeo...
Mycotoxin produced by Alternaria; topoisomerase...
MEK1/2 and Raf inhibitor.
p110α PI3K, DNA-PK, mTOR, Abl, Hck, Src, VEGFR...
Mouse selective STING agonist.
JAK1 inhibitor.
Synthetic peptide hormone, met-enkephalin analo...
pan-PI3K inhibitor
PP2A activator, Sphk1 and PKC inhibitor.
Pt-based DNA cross-linker.
Endogenous peptide hormone, involved in enteric...
Inhibitor of EGFR, HER2, and HER3.
Prodrug
Aminoglycoside; protein translation inhibitor.<...