Description
CCCP inhibits mitochondrial oxidative phosphorylation.
CCCP inhibits mitochondrial oxidative phosphorylation.
Cas No. | 555-60-2 |
---|---|
Purity | ≥99% |
Formula | C9H5ClN4 |
Formula Wt. | 204.62 |
IUPAC Name | 2-[(3-chlorophenyl)hydrazinylidene]propanedinitrile |
Synonym | Carbonyl cyanide m-chlorophenyl hydrazone; Carbonyl cyanide 3-chlorophenylhydrazone; m-Cl-CCP; Mesoxalonitrile 3-chlorophenylhydrazone |
Appearance | Brown powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Sanchez-Carbonel A, Mondragon B, Lopez-Chegne N, et al. The effect of the efflux pump inhibitor carbonyl cyanide m-chlorophenylhydrazone (CCCP) on the susceptibility to imipenem and cefepime in clinical strains of Acinetobacter baumannii. PLoS One. 2021 Dec 17;16(12):e0259915. PMID: 34919563
Koncha R, Ramachandran G, Sepuri N, et al. CCCP-induced mitochondrial dysfunction - characterization and analysis of integrated stress response to cellular signaling and homeostasis. FEBS J. 2021 Oct;288(19):5737-5754. PMID: 33837631
Chen S, Teng T, Zhang Z, et al. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) exhibits direct antibacterial activity against Mycobacterium abscessus. Infect Drug Resist. 2021 Mar 23;14:1199-1208. PMID: 33790590
Proteasome inhibitor.
Indole found in cruciferous vegetables; AhR ago...
Diterpene cafestol derivative found in coffee b...
Pentacyclic triterpene found in various plant s...
Laminin-derived nonapeptide.
Histamine H1 antagonist.
Nitrofuran, livestock antibiotic.
α-glucosidase inhibitor.
Tetracycline; FIASMA, histamine H1, 5-HT2, mACh...
Variety of flavonoid found in various plant sou...
Diterpene found in Taxus; potential microtubule...
Endogenous peptide fragment, involved in vasoco...
Acyclic nucleotide (adenosine) analog; viral DN...
Polymethoxy flavonoid found in citrus fruits.
Endogenous bombesin-related peptide, involved i...
Smoothened agonist.
Arylbenzimidazole; CHK2 inhibitor.
Statin; HMG-CoA reductase inhibitor, potential ...
Microtubule depolymerization inhibitor.
G-quadruplex ligand; DNA breakage inducer.