LKT Labs

Biochemicals for Life Science Research

Cetrorelix Acetate

Cetrorelix Acetate

Product ID C1879
Cas No. 130143-01-0
Purity ≥95%
Product Unit SizeCostQuantityStock
50 mg $1,968.00 Please Inquire
100 mg $2,679.00 Please Inquire
Bulk Quote

Quicklinks

Description

Cetrorelix is a gonadotropin-releasing hormone (GnRH) analog that inhibits LHRH and GnRH. Cetrorelix exhibits anti-inflammatory activity and has been used clinically as a treatment for infertility due to its suppression of FSH and LH levels. In animal models of benign prostatic hyperplasia (BPH), cetrorelix decreases levels of inflammatory cytokines and growth factors, decreasing prostate size and weight. Additionally, cetrorelix decreases levels of Bax, caspase 3, and cytochrome c, inhibiting chemotherapy-induced mitochondria-dependent apoptosis in granulosa cells in vivo.

Product Info

Cas No.

130143-01-0
Purity

≥95%
Formula

C70H92N17O14
Formula Wt.

1431.06
IUPAC Name

(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[ (2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl) propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl] amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(carbamoylamino)pentanoyl] amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N- [(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Synonym

Cetrelix Acetate, Cetrorenlin Acetate
Solubility

Soluble in DMSO.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

C1879 MSDS PDF
Info Sheet

C1879 Info Sheet PDF

References

Rick FG, Schally AV, Block NL, et al. LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia. Prostate. 2011 May 15;71(7):736-47. PMID: 20945403.

Zhao XJ, Huang YH, Yu YC, et al. GnRH antagonist cetrorelix inhibits mitochondria-dependent apoptosis triggered by chemotherapy in granulosa cells of rats. Gynecol Oncol. 2010 Jul;118(1):69-75. PMID: 20417958.

Reissmann T, Felberbaum R, Diedrich K, et al. Development and applications of luteinizing hormone-releasing hormone antagonists in the treatment of infertility: an overview. Hum Reprod. 1995 Aug;10(8):1974-81. PMID: 8567825.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N3323

    Nifuratel

    Nitrofuran derivative.

    ≥99%
  • C2916

    Chenodeoxycholic Acid

    Endogenous bile acid; FXR agonist.

    ≥98%
  • M9634

    Myriocin

    Atypical amino acid found in Isaria sinclairi, ...

    ≥99%, TLC
  • B1978

    Betulin-3-Acetate

    Pentacyclic triterpene found in various plant s...

    ≥97%
  • M8007

    Mubritinib, Free Base

    EGFR2 inhibitor.

    ≥99%
  • G4518

    Glucaric Acid Calcium Tetrahydrate

    Oxidized non-cylic hexose sugar.

    ≥98%
  • T3040

    Thienylpentyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • S7868

    SRT1720 Hydrochloride

    SIRT 1 activator, SIRT3 inhibitor.

    ≥98%
  • E6814

    Erdosteine

    Thiol derivative, antioxidant.

    ≥98%
  • B5075

    BMS-708163

    γ-Secretase inhibitor.

    ≥98%
  • I7458

    1-Isothiocyanato-9-(methylsulfinyl)-nonane

    ITC, sulforaphane analog.

    ≥98%
  • D3215

    Didymin

    Flavonoid glycoside found in citrus fruit.

    ≥98%
  • F4518

    Fleroxacin

    Fluoroquinolone; bacterial DNA gyrase and helic...

    ≥98%
  • R2714

    Recombinant HCV-NS5 Antigens

    Recombinant HCV antigen fragment.

    ≥95%
  • R3586

    Rivastigmine Tartrate

    AChE and BChE inhibitor.

    ≥99%
  • P3076

    PHT-427

    PDK1 and Akt inhibitor.

    ≥98%
  • H9712

    (E)-4-Hydroxytamoxifen

    SERM.

    ≥97%
  • B6902

    B-Raf IN 1

    B-Raf and c-Raf inhibitor.

    ≥98%
  • D1757

    L-Deoxyalliin

    Organosulfur found in garlic.

    ≥98%
  • B1853

    1,4-Benzoquinone

    Precursor in the synthesis of hydroquinone, ant...

    ≥98%