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Katacalcin

Product ID K0276
Cas No. 85916-47-8
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $129.80 In stock
1 mg $222.50 Please Inquire
2.5 mg $444.90 Please Inquire
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  • Product Info
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  • Description
  • Product Info
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Description

Katacalcin is a polypeptide encoded by the calc-1 gene that is also known as crustacean cardioactive peptide (CCAP or CCP1). Katacalcin exhibits immunomodulatory activity. Katacalcin activates PKA and decreases intracellular Ca2+ levels, inducing migration of CD14+ peripheral blood mononuclear cells and deactivating chemotaxis. Katacalcin may be used as a biomarker for medullary thyroid tumors. Additionally, this peptide may play a role in signaling cascade elicited by treatments for mood disorders, such as antipsychotic medications.

Product Info

Cas No.

85916-47-8

Purity

≥95%

Formula

C97H154N34O36S2

Formula Wt.

2436.64

Synonym

CCAP, CCP I, Calcitonin carboxyl-terminal flanking peptide

Solubility

Soluble in DMSO.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

K0276 MSDS PDF

Info Sheet

K0276 Info Sheet PDF

References

Kaneider NC, Egger P, Wiedermann FJ, et al. Involvement of cyclic adenosine monophosphate-dependent protein kinase A and pertussis toxin-sensitive G proteins in the migratory response of human CD14+ mononuclear cells to katacalcin. J Bone Miner Res. 2002 Oct;17(10):1872-82. PMID: 12369791.

Angelucci F, Gruber SH, Mathé AA. A pilot study of rat brain regional distribution of calcitonin, katacalcin and calcitonin gene-related peptide before and after antipsychotic treatment. Neuropeptides. 2001 Oct-Dec;35(5-6):285-91. PMID: 12030813.

Blind E, Raue F, Klaiber T, et al. Evaluation of sensitive PDN-21 (katacalcin) determination as tumor marker in medullary thyroid carcinoma. J Endocrinol Invest. 1992 Feb;15(2):93-8. PMID: 1569295.

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