Description
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
| Product Unit Size | Cost | Quantity | Stock |
|---|
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
| Cas No. | 305-03-3 |
|---|---|
| Purity | ≥99% |
| Formula | C14H19Cl2NO2 |
| Formula Wt. | 304.21 |
| Chemical Name | 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid |
| IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
| Synonym | Amboclorin, Leukeran |
| Melting Point | 64-66°C |
| Solubility | Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water. |
| Appearance | White to off white powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.
Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.
Endogenous alkaloid also found in citrus fruits...
Found in Cephalosporium; fatty acid synthase in...
Histamine H2 antagonist, GSK-3β inhibitor.
Labdane diterpene found in Coleus; PP2A and ade...
Endogenous peptide hormone fragment, involved i...
Peptide found in crustaceans; PKA activator.
CB1 agonist, TRPV1 agonist.
Anthraquinone found in various plant sources.
Synthetic antioxidant that induces phase II enz...
Isoquinoline alkaloid found in a variety of pla...
Nitrogen mustard, DNA alkylator.
Thienylbutyl ITC analog.
Tricyclic antidepressant; potential D1/2 antago...
OVA antigen.
Imidazothiazole; alkaline phosphatase inhibitor...
Penciclovir prodrug, nucleoside (guanosine) ana...
Terpene lactone found in Ginkgo; GlyR antagonis...
Endogenous amino sugar precursor required for p...
Taxane synthesis intermediate.
CHK1 inhibitor.