Description
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Product Unit Size | Cost | Quantity | Stock |
---|
Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).
Cas No. | 305-03-3 |
---|---|
Purity | ≥99% |
Formula | C14H19Cl2NO2 |
Formula Wt. | 304.21 |
Chemical Name | 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid |
IUPAC Name | 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid |
Synonym | Amboclorin, Leukeran |
Melting Point | 64-66°C |
Solubility | Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water. |
Appearance | White to off white powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.
Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.
FGFR inhibitor.
GSK3 inhibitor.
Catalyzes hydrolysis of asparagine.
Benzopyrone found in various plants, precursor ...
Kavalactone originally found in Piper methystic...
Cholesterol ester transfer protein inhibitor.
Oltipraz analog, salivary gland secretion enhan...
5-Nitroimidazole derivative; genotoxic.
H+/K+ ATPase inhibitor.
Endogenous pyrimidine base required for product...
TRPC5, NS4B, histamine H1 inhibitor.
CHK1 inhibitor.
Vitamin B6 derivative, antioxidant.
ALK5 (activin-like) inhibitor.
Taxoid that disrupts the microtubular network i...
Diterpene found in coffee beans.
CHK1 inhibitor.
NSAID; COX-2 inhibitor.
Triterpene saponin found in Panax.
CRM1/XPO1 inhibitor.