Name: Chlorambucil
SKU: C2946
Availability: InStock

Description

Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).

Product Info

Cas No.	305-03-3
Purity	≥98%
Formula	C₁₄H₁₉Cl₂NO₂
Formula Wt.	304.21
Chemical Name	4-[Bis(2-chloroethyl)amino]benzenebutanoic acid
IUPAC Name	4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid
Synonym	Amboclorin, Leukeran
Melting Point	64-66°C
Solubility	Soluble in alcohol, chloroform or acetone (500 mg/mL). Insoluble in water.
Appearance	White to off white powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	C2946 MSDS PDF
Info Sheet	C2946 Info Sheet PDF

References

Begleiter A, Mowat M, Israels LG, et al. Chlorambucil in chronic lymphocytic leukemia: mechanism of action. Leuk Lymphoma. 1996 Oct;23(3-4):187-201. PMID: 9031099.

Kundu GC, Schullek JR, Wilson IB. The alkylating properties of chlorambucil. Pharmacol Biochem Behav. 1994 Nov;49(3):621-4. PMID: 7862715.

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Chlorambucil

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