• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
CKS-17

CKS-17

Product ID C4274
Cas No. 99273-04-8
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $68.30 In stock
1 mg $126.00 In stock
2.5 mg $252.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

CKS-17 is a synthetic peptide with a sequence homologous to endogenous retroviral transmembrane envelope proteins; it exhibits immunosuppressive activity in vitro and in vivo. In one study, CKS-17 inhibits production of IL-12, IL-2, TNF-α, and IFN-γ, increases levels of cAMP and IL-10, and activates ERK1/2, MEK, PKD, PLC-γ, and c-Raf; this results in an inhibition of the Th1-centric immune response.

Product Info

Cas No.

99273-04-8

Purity

≥95%

Formula

C87H148N26O24

Formula Wt.

1942.31

Synonym

Envelope Glycoprotein; Env Polyprotein; CKS 17; CKS17.

Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

C4274 Info Sheet PDF

References

Haraguchi S, Good RA, Day-Good NK. A potent immunosuppressive retroviral peptide: cytokine patterns and signaling pathways. Immunol Res. 2008;41(1):46-55. PMID: 18506644.

Fan Tx, Day NK, Luangwedchakarn V, et al. The phosphorylation of phospholipase C-gamma1, Raf-1, MEK, and ERK1/2 induced by a conserved retroviral peptide. Peptides. 2005 Nov;26(11):2165-74. PMID: 15978701.

Takahashi A, Day NK, Luangwedchakarn V, et al. A retroviral-derived immunosuppressive peptide activates mitogen-activated protein kinases. J Immunol. 2001 Jun 1;166(11):6771-5. PMID: 11359835.

Kabeya H, Ohashi K, Sugimoto C, et al. Bovine leukaemia virus envelope peptides cause immunomodulation in BALB/c mice. Vet Immunol Immunopathol. 1999 Mar 29;68(1):39-48. PMID: 10231950.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B3300

    BI-6727

    PLK1 inhibitor.

    ≥99%
  • E5057

    Emodin

    Anthraquinone found in various plant sources; C...

    ≥95%
  • T6833

    Triacetyl Aloe-emodin (Impurity A)

    Derivative of aloe-emodin, anthraquinone found ...

    ≥98%
  • C5592

    CNX-774

    BTK inhibitor.

    ≥98%
  • T3036

    Thienylhexyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥97%
  • S0278

    Satraplatin

    Pt-based DNA cross-linker.

    ≥98%
  • P2922

    Phenylhexyl Isothiocyanate

    ITC found in cruciferous vegetables; HDAC inhib...

    ≥98%
  • P0268

    Parasin I

    Histone H2-derived antimicrobial peptide found ...

    ≥95%
  • B5044

    BML-277

    Arylbenzimidazole; CHK2 inhibitor.

    ≥98%
  • P4560

    Proteolipid Protein (139-151)

    Immunodominant peptide fragment of PLP, used to...

    ≥95%
  • U7354

    Usnic Acid

    Dibenzofuran produced by lichens.

    ≥98%
  • R0109

    Racecadotril

    Enkephalinase inhibitor.

    ≥98%
  • E4417

    Eledoisin Related Peptide

    Peptide, substance P analog; NK agonist.

    ≥95%
  • W0270

    (±)-Warfarin Sodium Clathrate

    Coumarin; VKORC1 inhibitor.

    ≥98%
  • F1895

    Fexofenadine Hydrochloride

    Histamine H1 antagonist.

    ≥98%
  • R2711

    Recombinant HCV-Core Antigens

    Recombinant HIV core protein antigen fragment.<...

    ≥95%
  • B1855

    O6-Benzylguanine

    MGMT inhibitor.

    ≥98%
  • M1678

    2-Methoxyestradiol

    Estradiol metabolite; microtubule depolymerizat...

    ≥98%
  • I5830

    Iohexol

    Low osmolarity contrast agent used for imaging ...

    ≥98%
  • V0274

    [Lys8]-Vasopressin

    Peptide, vasopressin analog; V1/2 agonist.

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only