Description
CV-66 is a 1,8-Diaza-anthracene-tetrone compound that exhibits anticancer activity, inhibiting activation of JNK and ERK5 and suppressing proliferation in various tumor cell lines.
CV-66 is a 1,8-Diaza-anthracene-tetrone compound that exhibits anticancer activity, inhibiting activation of JNK and ERK5 and suppressing proliferation in various tumor cell lines.
| Purity | ≥60% |
|---|---|
| Formula | C14H10N2O4 |
| Formula Wt. | 270.24 |
| Chemical Name | 3,7-Dimethyl-9-oxido-1H-pyrido[3,2-g]quinolin-9-ium-2,5,10-trione |
| IUPAC Name | 3,7-dimethyl-9-oxido-1H-pyrido[3,2-g]quinolin-9-ium-2,5,10-trione |
| Synonym | Diazaanthraquinone N-oxide |
| Appearance | Orange Solid |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet | |
| Brochures |
Pipaón C, Gutierrez P, Montero JC, et al. Mitogen-activated protein kinase routes as targets in the action of diaza-anthracene compounds with a potent growth-inhibitory effect on cancer cells. Mol Cancer Ther. 2002 Aug;1(10):811-9. PMID: 12492114.
Synthesis intermediate
Pyrimidine analog, fluorouracil derivative; thy...
SIRT1/2 inhibitor.
Steroidal alkaloid found in Veratrum and Fritil...
Prolyl hydroxylase inhibitor.
Indoline; PDGFR, VEGFR, c-KIT, FLT3, mTORC1 inh...
Naphthoquinone found in Plumbago.
Expectorant.
EGFR (T790M) inhibitor.
Endogenous peptide hormone, involved in growth ...
Dihydrofolate reductase inhibitor.
Snake venom cardiotoxin found in Naja naja atra...
GPR84 agonist.
Renin inhibitor.
Glycosaminoglycan
Peptide toxin found in Conus snails; nAChR inhi...
Proteasome inhibitor.
GSK3 inhibitor.
LRRK2 inhibitor.
Selective inhibitor of cytochrome P450 1B1 (CYP...