LKT Labs

Biochemicals for Life Science Research

Cyclophosphamide Monohydrate

Cyclophosphamide Monohydrate

Product ID C9609
Cas No. 6055-19-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $71.00 In stock
5 g $210.00 In stock
Bulk Quote

Quicklinks

Description

Cyclophosphamide is a nitrogen mustard that acts as an alkylator, adding alkyl groups to the N7 nitrogen of guanine bases; this inhibits DNA repair and replication. Cyclophosphamide exhibits anticancer chemotherapeutic and immunomodulatory activities. This compound is one component in the CHOP chemotherapy regimen. Cyclophosphamide is clinically used to treat various cancers, graft-versus-host disease (GvHD), and autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematous (SLE).

Product Info

Cas No.

6055-19-2
Purity

≥98%
Formula

C7H15Cl2N2O2P • H2O
Formula Wt.

279.10
Chemical Name

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-ox- azaphosphorin-2-amine 2 oxide monohydrate
IUPAC Name

N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine;hydrate
Synonym

Cycloblastin, Cyclostin, Cytoxan, Endoxan

Melting Point

41-45°C
Solubility

Soluble in water. Slightly soluble in ethanol.
Appearance

White crystalline powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

C9609 MSDS PDF
Info Sheet

C9609 Info Sheet PDF

References

Sistigu A, Viaud S, Chaput N, et al. Immunomodulatory effects of cyclophosphamide and implementations for vaccine design. Semin Immunopathol. 2011 Jul;33(4):369-83. PMID: 21611872.

Makhani N, Gorman MP, Branson HM, et al. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009 Jun 16;72(24):2076-82. PMID: 19439723.

Hall AG, Tilby MJ. Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Rev. 1992 Sep;6(3):163-73. PMID: 1422285.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F8147

    Fulvestrant

    Induces ER degradation.

    ≥98%
  • A0963

    Adrenocorticotropic Hormone (1-10), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • C9863

    Cyproconazole

    Triazole; 14-α demethylase inhibitor, voltage-...

    ≥95%
  • D3362

    Dipyridamole

    PDE and adenosine deaminase inhibitor.

    ≥98%
  • O9396

    Oxytetracycline

    Tetracycline; protein translation inhibitor.

    ≥96%
  • S9775

    Systemin

    Peptide hormone found in Solanaceae family plan...

    ≥95%
  • E6397

    EPZ6438

    Potent and selective inhibitor

    ≥98%
  • S7717

    Sterigmatocystin

    Mycotoxin produced by Aspergillus; carcinogen.<...

    ≥98%
  • C0365

    Carvedilol

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • C0221

    Caffeine

    Xanthine alkaloid found in coffee, tea, and oth...

    ≥98%
  • T0090

    7-(Triethylsilyl)-baccatin III

    Synthetic taxol synthesis intermediate; microtu...

    ≥98%
  • M7530

    [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone

    Semi-synthetic peptide, melanocortin analog; MC...

    ≥98%
  • S1968

    Seratrodast

    TxA2 antagonist.

    ≥99%
  • E6232

    (−)-Epicatechin Gallate

    Flavanol originally found in Camilla (green tea...

    ≥98%
  • B0246

    Balofloxacin Dihydrate

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • L3453

    Linezolid

    Oxazolidinone; protein synthesis inhibitor.

    ≥99%
  • O1078

    Octreotide Acetate

    Somatostatin analog, peptide; somatostatin agon...

    ≥95%
  • L5751

    Lomerizine Dihydrochloride

    L-type and T-type Ca2+ and TRP antagonist.

    ≥98%
  • A7461

    Asperosaponin VI

    Triterpene saponin found in Dipsacus asper.

    ≥98%
  • D1757

    L-Deoxyalliin

    Organosulfur found in garlic.

    ≥98%