LKT Labs

Biochemicals for Life Science Research

Cyclophosphamide Monohydrate

Product ID C9609
Cas No. 6055-19-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $68.00 In stock
5 g $200.00 In stock
Bulk Quote

Quicklinks

Description

Cyclophosphamide is a nitrogen mustard that acts as an alkylator, adding alkyl groups to the N7 nitrogen of guanine bases; this inhibits DNA repair and replication. Cyclophosphamide exhibits anticancer chemotherapeutic and immunomodulatory activities. This compound is one component in the CHOP chemotherapy regimen. Cyclophosphamide is clinically used to treat various cancers, graft-versus-host disease (GvHD), and autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematous (SLE).

Product Info

Cas No.

6055-19-2
Purity

≥98%
Formula

C7H15Cl2N2O2P • H2O
Formula Wt.

279.10
Chemical Name

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-ox- azaphosphorin-2-amine 2 oxide monohydrate
IUPAC Name

N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine;hydrate
Synonym

Cycloblastin, Cyclostin, Cytoxan, Endoxan

Melting Point

41-45°C
Solubility

Soluble in water. Slightly soluble in ethanol.
Appearance

White crystalline powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

C9609 MSDS PDF
Info Sheet

C9609 Info Sheet PDF

References

Sistigu A, Viaud S, Chaput N, et al. Immunomodulatory effects of cyclophosphamide and implementations for vaccine design. Semin Immunopathol. 2011 Jul;33(4):369-83. PMID: 21611872.

Makhani N, Gorman MP, Branson HM, et al. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009 Jun 16;72(24):2076-82. PMID: 19439723.

Hall AG, Tilby MJ. Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Rev. 1992 Sep;6(3):163-73. PMID: 1422285.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • W7200

    WS3

    Islet β cell proliferation stimulator.

    ≥98%
  • T3584

    Tivantinib

    MET and GSK-3α/β inhibitor.

    ≥98%
  • S0278

    Satraplatin

    Pt-based DNA cross-linker.

    ≥98%
  • O4532

    Oligomycin B

    Macrolide; F1F0 ATP synthase inhibitor.

    ≥97%, TLC, HPLC
  • M3321

    Mifepristone

    Synthetic steroid, contraceptive; PR and glucoc...

    ≥98%
  • A990144

    AZD4320

    Inhibitor of Bcl-2 and Bcl-xL

    ≥99%
  • P0145

    Palmitoyl-D,L-carnitine

    Long chain acylcarnitine involved in fatty acid...

    ≥98%
  • V3455

    Vinpocetine

    Targets nuclear factor kappa B activation.

    ≥98%
  • I0418

    Iberverin

    ITC found in cruciferous vegetables, homolog of...

    ≥98%
  • N5986

    Novobiocin Sodium

    Aminocoumarin; bacterial DNA gyrase inhibitor.<...

    ≥98%
  • G5874

    Gossypol

    Polyphenol found in Gossypium; calcineurin and ...

    ≥98%
  • A0922

    Acetyl-L-Carnitine Hydrochloride

    Carnitine derivative, involved in energy homeos...

    ≥98%
  • G3553

    Ginsenoside Rb2

    Triterpene saponin found in species of Panax.

    ≥98%
  • P3542

    PIK-93

    p110α and p110γ PI3K inhibitor.

    ≥98%
  • R0243

    Raloxifene Hydrochloride

    SERM.

    ≥98%
  • X4424

    XL-765

    PI3K and mTOR inhibitor.

    ≥98%
  • S881011

    Swainsonine

    Antineoplastic immunomodulator.

    ≥98%
  • T7197

    Tryprostatin A

    Diketopiperazine produced by Aspergillus; micro...

    ≥92%
  • B011458

    Baloxavir

    Cap-dependent endonuclease inhibitor

    ≥ 99%
  • T1652

    Teniposide

    Podophyllotoxin derivative; topoisomerase II in...

    ≥97%