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Cyclosporin D

Cyclosporin D

Product ID C9613
Cas No. 63775-96-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $117.70 In stock
5 mg $354.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cyclosporin D is a cyclosporin metabolite that weakly inhibits calmodulin and displays little immunosuppressive activity. Cyclosporin D exhibits anti-parasitic and antimalarial activities, inhibiting Plasmodium development in vitro and in vivo.

Product Info

Cas No.

63775-96-2

Purity

≥98%

Formula

C63H113N11O12

Formula Wt.

1216.64

IUPAC Name

(3S,6S,9S,12R,15S,18S,21S,24S,30S)-33-[(E,1R, 2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6, 9,18,24-tetrakis(2-methylpropyl)-3,21,30-tri(propan-2-yl)-1,4,7,10,13, 16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26, 29,32-undecone

Synonym

Val2-cyclosporine

Melting Point

148-151°C

Solubility

Soluble in methanol, ethanol, acetone, ether, ethyl acetate or chloroform. Insoluble in water.

Appearance

White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C9613 MSDS PDF

Info Sheet

C9613 Info Sheet PDF

References

Uadia PO, Ezeamuzie IC, Ladan MJ, et al. Antimalarial activity of cyclosporins A, C and D. Afr J Med Med Sci. 1994 Mar;23(1):47-51. PMID: 7839946.

Sadeg N, Pham-Huy C, Rucay P, et al. In vitro and in vivo comparative studies on immunosuppressive properties of cyclosporines A, C, D and metabolites M1, M17 and M21. Immunopharmacol Immunotoxicol. 1993 Mar-Jun;15(2-3):163-77. PMID: 8349948.

Custom Order

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