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Cysteamine Hydrochloride

Cysteamine Hydrochloride

Product ID C9673
Cas No. 156-57-0
Purity ≥99%
Product Unit SizeCostQuantityStock
25 g $75.10 In stock
100 g $225.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cysteamine is an aminothiol that exhibits antioxidative, anti-metastatic, antidepressant, neuromodulatory, and antipsychotic activities. Cysteamine is used in research models to induce ulcer formation; clinically, it treats cystinosis and other disorders of cysteine excretion. Cysteamine is also a component used to form coenzyme A (CoA). In animal models of pancreatic cancer, cysteamine decreases activity of matrix metalloproteinases (MMPs) and suppresses metastasis. Cysteamine decreases immobility time in animals undergoing the forced swim test and tail suspension test and increases levels of BDNF. This compound also displays potential benefit in pre-clinical models of schizophrenia. Additionally, cysteamine improves motor deficits and increases survival in animal models of Huntington’s disease.

Product Info

Cas No.

156-57-0

Purity

≥99%

Formula

C2H7NS • HCl

Formula Wt.

113.61

Chemical Name

2-Aminoethanothiol hydrochloride

IUPAC Name

2-aminoethanethiol;hydrochloride

Synonym

Mercaptamine, Decarboxycysteine, MEA, Mercamine, Becaptan

Melting Point

70.2-70.7°C

Solubility

Soluble in water or ethanol.

Appearance

White powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C9673 MSDS PDF

Info Sheet

C9673 Info Sheet PDF

References

Khomenko T, Deng X, Ahluwalia A, et al. STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration. Dig Dis Sci. 2014 Feb;59(2):297-306. PMID: 24385009.

Fujisawa T, Rubin B, Suzuki A, et al. Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer. PLoS One. 2012;7(4):e34437. PMID: 22532830.

Shieh CH, Hong CJ, Huang YH, et al. Potential antidepressant properties of cysteamine on hippocampal BDNF levels and behavioral despair in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1590-4. PMID: 18582526.

Pae CU, Lee C, Paik IH. Therapeutic possibilities of cysteamine in the treatment of schizophrenia. Med Hypotheses. 2007;69(1):199-202. PMID: 17166669.

Mao Z, Choo YS, Lesort M. Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells. Eur J Neurosci. 2006 Apr;23(7):1701-10. PMID: 16623826.

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