LKT Labs

Biochemicals for Life Science Research

Cytarabine

Cytarabine

Product ID C9778
Cas No. 147-94-4
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $52.20 In stock
500 mg $138.50 In stock
1 g $225.30 In stock
Bulk Quote

Quicklinks

Description

Cytarabine is a cytosine nucleoside analog that exhibits anticancer chemotherapeutic and antiviral activities. This antimetabolite is clinically used to treat chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), and non-Hodgkin lymphoma. Cytarabine inhibits RNA polymerase and DNA polymerase, preventing DNA synthesis. Although it is too toxic for antiviral use, cytarabine inhibits the growth or replication of herpesviruses such as varicella-zoster and cytomegalovirus (CMV).

Product Info

Cas No.

147-94-4
Purity

≥98%
Formula

C9H13N3O5
Formula Wt.

243.22
Chemical Name

4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
IUPAC Name

4-amino-1-[(2R,3S,4S,5R)-3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym

Alexan, Arabitin, Ara-C, Cytosar, Erpalfa, Iretin, Udicil
Melting Point

212-213°C
Solubility

Soluble in water to 100 mM, DMSO to 50 mM, ethanol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

C9778 MSDS PDF
Info Sheet

C9778 Info Sheet PDF

References

Abdel-Aziz W, Jiang HY, Hickey RJ, et al. Ara-C affects formation of cancer cell DNA synthesome replication intermediates. Cancer Chemother Pharmacol. 2000;45(4):312-9. PMID: 10755320.

Hiddemann W. Cytosine arabinoside in the treatment of acute myeloid leukemia: the role and place of high-dose regimens. Ann Hematol. 1991 Apr;62(4):119-28. PMID: 2031974.

Lauter CB, Bailey EJ, Lerner AM. Assessment of cytosine arabinoside as an antiviral agent in humans. Antimicrob Agents Chemother. 1974 Nov;6(5):598-602. PMID: 15825312.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T3203

    Tianeptine Sodium Hydrate

    μOR and δOR agonist, D2/D3 DA potentiator.

    ≥98%
  • A4547

    Alloxan Monohydrate

    Pyrimidine, glucose analog, used to induce diab...

    ≥98%
  • T6935

    Trimebutine Base

    BK K+ channel and L-type Ca2+ channel blocker.<...

    ≥97%
  • L1044

    LCL-161

    SMAC mimetic; PXR agonist, IAP inhibitor.

    ≥99%, ≥99%ee, de
  • A8070

    Auraptene

    Monoterpene coumarin ether found in Citrus; PPA...

    ≥98%
  • H9803

    Hyaluronic Acid Sodium (0.2 -5 kDA)

    Glycosaminoglycan
  • O4531

    Oligomycin A

    Macrolide; F1F0 ATP synthase inhibitor.

    ≥97%, TLC, HPLC
  • C0800

    C59

    PORCN inhibitor.

    ≥98%
  • C4759

    Clozapine N-oxide

    Inert clozapine analog, activates specialized G...

    ≥98%
  • E4417

    Eledoisin Related Peptide

    Peptide, substance P analog; NK agonist.

    ≥95%
  • C9613

    Cyclosporin D

    Cyclosporin metabolite; weak calmodulin inhibit...

    ≥98%
  • G3355

    Ginkgolide B

    Terpene lactone found in Ginkgo; GlyR antagonis...

    ≥98%
  • S0048

    Salicin

    Alcoholic β-glucoside found in willow bark, sa...

    ≥98%
  • A5033

    4-Aminosalicylic Acid

    Dihydrofolate reductase inhibitor.

    ≥98%
  • R0212

    Radicicol

    Benzoquinone ansamycin; topoisomerase VI-B, HSP...

    ≥96%
  • V1870

    Verruculogen

    Mycotoxin produced by Aspergillus; BK K+ channe...

    ≥95%
  • S771337

    STING Agonist-1

    Indirect activator of STING signaling

    ≥98%
  • G1650

    Geniposide

    Iridoid glycoside found in Gardenia.

    ≥98%
  • I7459

    1-Isothiocyanato-8-(methylsulfinyl)-octane

    ITC found in Nasturtium officinale (watercress)...

    ≥98%
  • H5748

    D,L-Homocysteine Thiolactone Hydrochloride

    Heterocyclic derivative of cysteine, alters pro...

    ≥99%