• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Pipemidic Acid

Pipemidic Acid

Product ID P3461
Cas No. 51940-44-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $52.50 In stock
10 g $89.70 In stock
100 g $561.40 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Pipemidic acid is a pyridopyrimidine antibiotic that inhibits bacterial DNA gyrase; it exhibits antibacterial activity. Pipemidic acid also inhibits ATP-sensitive K+ channels, inducing insulin release in vitro, suggesting potential a potential link to hypoglycemia. High doses of pipemidic acid induce cartilage toxicity (arthropathy) in neonatal mice.

Product Info

Cas No.

51940-44-4

Purity

≥98%

Formula

C14H17N5O3

Formula Wt.

303.32

Chemical Name

8-ethyl-5-oxo-2-piperazin-1-ylpyrido[2,3-d]pyrimidine-6-carboxylic acid

IUPAC Name

8-ethyl-5-oxo-2-piperazin-1-ylpyrido[2,3-d]pyrimidine-6-carboxylic acid

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P3461 MSDS PDF

Info Sheet

P3461 Info Sheet PDF

References

Aubry A, Pan XS, Fisher LM, et al. Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity. Antimicrob Agents Chemother. 2004 Apr;48(4):1281-8. PMID: 15047530.

Maeda N, Tamagawa T, Niki I, et al. Increase in insulin release from rat pancreatic islets by quinolone antibiotics. Br J Pharmacol. 1996 Jan;117(2):372-6. PMID: 8789393.

Linseman DA, Hampton LA, Branstetter DG. Quinolone-induced arthropathy in the neonatal mouse. Morphological analysis of articular lesions produced by pipemidic acid and ciprofloxacin. Fundam Appl Toxicol. 1995 Nov;28(1):59-64. PMID: 8566484.

Aoyama H, Sato K, Fujii T, et al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32(1):104-9. PMID: 2831810.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A1592

    ADX-47273

    mGluR5 positive modulator.

    ≥98%
  • R0249

    Ramipril

    ACE inhibitor.

    ≥98%
  • D1768

    Dermaseptin I

    Cationic antimicrobial peptide, alters bacteria...

    ≥96%
  • I7256

    Isobavachalcone

    Prenylated chalcone flavonoid found in Psoralea...

    ≥97%
  • E6825

    Ergosterol

    Sterol cell membrane component found in yeast a...

    ≥96%
  • A5035

    5-Aminosalicylic Acid

    Salicylic acid derivative; PPARγ agonist, pote...

    ≥98%
  • E7356

    Esomeprazole Magnesium Trihydrate

    S-isomer of omeprazole; H+/K+ ATPase inhibitor....

    ≥99%
  • C4559

    Clomiphene Citrate

    Used for in vitro fertilization; FIASMA, SERM.<...

    ≥98%
  • M174446

    Meleagrin

    FabI inhibitor

    ≥99%
  • E5358

    Enoxacin

    Fluoroquinolone; vacuolar H+ ATPase, topoisomer...

    ≥98%
  • V014463

    Valsartan Methyl Ester

    Valsartan impurity

    ≥98%
  • A5301

    Anacetrapib

    Cholesterol ester transfer protein inhibitor.

    ≥98%
  • V0147

    Valproic Acid Sodium

    T-type Ca2+ and voltage-gated Na+ channel block...

    ≥98%
  • P3542

    PIK-93

    p110α and p110γ PI3K inhibitor.

    ≥98%
  • T3100

    Thyrotropin-releasing Hormone

    Endogenous tripeptide, involved in HPA signalin...

    ≥95%
  • C2949

    Chlorpheniramine Maleate

    Alkylamine; histamine H1 antagonist, SERT and N...

    ≥98%
  • C8500

    CV-65

    1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...

    ≥70%
  • A724092

    Asciminib Hydrochloride

    Allosteric inhibitor

    ≥98%
  • C5863

    Coptisine Chloride, natural

    Isoquinoline alkaloid found in a variety of pla...

    ≥98%
  • O1176

    n-Octyl Caffeate

    Caffeic acid derivative.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only