• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
6-Aminonicotinamide

6-Aminonicotinamide

Product ID A4940
Cas No. 329-89-5
Purity ≥98%
Product Unit SizeCostQuantityStock
250 mg $67.80 In stock
1 g $142.80 In stock
5 g $413.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

6-Aminonicotinamide inhibits glucose-6-phosphate dehydrogenase and suppresses activity in the pentose phosphate pathway. This compound exhibits potential anticancer benefit, inducing apoptosis and inhibiting the growth of cancer cells when combined with 2-deoxy-D-glucose. In vitro, 6-aminonicotinamide prevents maturation of oocytes.

Product Info

Cas No.

329-89-5

Purity

≥98%

Formula

C6H7N3O

Formula Wt.

137.14

Chemical Name

6-Aminopyridine-3-carboxamide

IUPAC Name

6-aminopyridine-3-carboxamide

Synonym

6-Aminopyridine-3-carboxamide

Melting Point

245-248°C

Solubility

DMSO; or MeOH, 0.2/20, clear after heating

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A4940 MSDS PDF

Info Sheet

A4940 Info Sheet PDF

References

Parkhitko AA, Priolo C, Coloff JL, et al. Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide. Mol Cancer Res. 2014 Jan;12(1):48-57. PMID: 24296756.

Alvarez GM, Ferretti EL, Gutnisky C, et al. Modulation of glycolysis and the pentose phosphate pathway influences porcine oocyte in vitro maturation. Reprod Domest Anim. 2013 Aug;48(4):545-53. PMID: 23189959.

Preuss J, Richardson AD, Pinkerton A, et al. Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors. J Biomol Screen. 2013 Mar;18(3):286-97. PMID: 23023104.

Bhardwaj R, Sharma PK, Jadon SP, et al. A combination of 2-deoxy-D-glucose and 6-aminonicotinamide induces cell cycle arrest and apoptosis selectively in irradiated human malignant cells. Tumour Biol. 2012 Aug;33(4):1021-30. PMID: 22328137.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • O4549

    Olmesartan Medoxomil

    AT1 inhibitor.

    ≥98%
  • M3584

    Mivacurium

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • C4557

    Clofibrate

    Fibrate; PPARα agonist.

    ≥99%
  • U5232

    Uniconazole

    Triazole; gibberellin inhibitor, potential 14-Î...

    ≥98%
  • G2868

    Ghrelin, human

    Endogenous peptide hormone, involved in feeding...

    ≥98%
  • D3420

    4-(3,4-Difluorobenzo)curcumin

    Curcumin derivative.

    ≥95%
  • R1217

    RDEA119

    MEK1/2 inhibitor.

    ≥98%
  • A7204

    AS-605240

    p110δ PI3K inhibitor.

    ≥98%
  • C0245

    Calcitonin Gene Related Peptide, rat

    Endogenous calcitonin-family peptide, involved ...

    ≥95%
  • E6356

    Epothilone D

    Microtubule depolymerization inhibitor.

    ≥98%
  • T1010

    7-Acetyl Paclitaxel

    Synthesis impurity

    ≥98%
  • A480020

    (R,S)-AM 1241

    Cannabinoid receptor 2 selective agonist.

    ≥96%
  • H3273

    Histatin 5

    Endogenous antimicrobial peptide, binds bacteri...

    ≥95%
  • U6901

    Uracil

    Endogenous pyrimidine base required for product...

    ≥98%
  • I5213

    Indole-3-carbinol

    Indole, glucosinolate found in cruciferous vege...

    ≥98%
  • I7759

    Isoxanthohumol

    Prenylflavinoid, derivative of xanthohumol foun...

    ≥98%
  • C0261

    Captopril

    ACE inhibitor.

    ≥98%
  • N1757

    Neostigmine Bromide

    AChE inhibitor.

    ≥92%
  • V1854

    Venlafaxine Hydrochloride

    SERT, NET, MAO inhibitor.

    ≥98%
  • C0260

    Capsanthin

    Carotenoid originally found in Capsicum. Color ...

    Color value:100

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only