• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
cGAMP Disodium [STING Ligand]

cGAMP Disodium [STING Ligand]

Product ID G0250
Cas No. 2407516-83-8, 849214-04-6 (free acid)
Purity ≥98%
Product Unit SizeCostQuantityStock
100 µg $102.90 In stock
500 µg $299.30 In stock
1 mg $551.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

cGAMP is a cyclic dinucleotide that functions as an endogenous second messenger that detects cytosolic DNA and induces STING-dependent interferon type 1 responses. cGAMP exhibits immunostimulatory activity and acts as an adjuvant. This compound enhances adaptive immune responses by increasing antigen-specific IgG levels in vivo.

Product Info

Cas No.

2407516-83-8, 849214-04-6 (free acid)

Purity

≥98%

Formula

C20H24N10O13P2・Na2

Formula Wt.

718.37

Chemical Name

3',3'-cGAMP disodium

IUPAC Name

disodium;2-amino-9-[(1S,6R,8R,9R,10S,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-dihydroxy-3,12-dioxido-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3λ5,12λ5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]-1H-purin-6-one

Synonym

cyclic (adenosine monophosphate-guanosine monophosphate), cyclic GMP-AMP, c-(GpAp), 3',3'-cGAMP

Solubility

Soluble in water.

Appearance

Crystalline solid.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G0250 MSDS PDF

Info Sheet

G0250 Info Sheet PDF

References

Ma F, Li B, Liu SY, et al. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS. J Immunol. 2015 Feb 15;194(4):1545-54. PMID: 25609843.

Škrnjug I, Guzmán CA, Rueckert C. Cyclic GMP-AMP displays mucosal adjuvant activity in mice. PLoS One. 2014 Oct 8;9(10):e110150. Erratum in: PLoS One. 2015;10(3):e0123605. Ruecker, Christine [corrected to Rueckert, Christine]. PMID: 25295996.

Wu J, Sun L, Chen X, et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science. 2013 Feb 15;339(6121):826-30. PMID: 23258412.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B5044

    BML-277

    Arylbenzimidazole; CHK2 inhibitor.

    ≥98%
  • T3305

    Tibolone

    Synthetic steroid hormone used in HRT; SERM, PR...

    ≥98%
  • D0169

    Darifenacin Hydrobromide

    M3 mAChR antagonist.

    ≥98%
  • C0171

    Carboplatin

    Pt-based DNA cross-linker.

    ≥99%
  • T342710

    Tirzepatide

    GLP-1/GIP receptor co-agonist

    ≥98%
  • C2946

    Chlorambucil

    Nitrogen mustard, DNA alkylator.

    ≥99%
  • S1845

    L-(+)-Selenomethionine

    Naturally occurring amino acid found in grains,...

    ≥98%
  • T0093

    2′-Acetyltaxol

    Taxane synthesis intermediate.

    ≥98%
  • L5873

    Losartan Potassium

    AT1 antagonist.

    ≥98%
  • V5886

    Voriconazole

    Triazole; 14α demethylase inhibitor.

    ≥98%
  • Z1602

    Zearalenone

    Mycotoxin produced by Fusarium; ER agonist.

    ≥98%
  • L0528

    LBH-589

    HDAC1/2/3/11 inhibitor.

    ≥98%
  • T3310

    Ticlopidine Hydrochloride

    Thienopyridine; P2Y12 antagonist.

    ≥98%
  • T0099

    10-Deacetylbaccatin-III

    Diterpene found in Taxus.

    ≥98%
  • G7242

    GSK-690693

    Akt inhibitor.

    ≥99%
  • B3374

    Bisacodyl

    Diphenylmethane derivative, stimulates colonic ...

    ≥98%
  • G7862

    GTPL-5846

    GPR84 agonist.

    ≥98%
  • O0400

    Obatoclax

    BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.

    ≥98%
  • G3461

    Ginsenoside F2

    Triterpene saponin found in species of Panax.

    ≥98%
  • A0964

    Adrenocorticotropic Hormone (1-13), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only