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10-Deacetylbaccatin-III

10-Deacetylbaccatin-III

Product ID T0099
Cas No. 32981-86-5
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $555.60 In stock
10 mg $888.70 In stock
25 mg $1,735.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

10-Deacetybaccatin III is a diterpene found in Taxus that exhibits analgesic, anti-inflammatory, and anti-parasitic activities. In vivo, this compound decreases edema as well as pain scores in the acid-induced writing test. 10-Deacetylbaccatin III also induces G2/M phase cell cycle arrest and inhibits growth in Leishmania.

Product Info

Cas No.

32981-86-5

Purity

≥98%

Formula

C29H36O10

Formula Wt.

544.59

IUPAC Name

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12,15-tetrahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

Synonym

10-DB III, 10-Deacetylbaccatine III, Docetaxel impurity E; 10-deacetylbaccatin; 10-deacetyl-baccatin; 10-DAB.

Melting Point

230-233°C

Solubility

Soluble in DMSO.

Appearance

White to off white crystalline powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T0099 MSDS PDF

Info Sheet

T0099 Info Sheet PDF

References

Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6. PMID: 21953729.

Georgopoulou K, Smirlis D, Bisti S, et al. In vitro activity of 10-deacetylbaccatin III against Leishmania donovani promastigotes and intracellular amastigotes. Planta Med. 2007 Aug;73(10):1081-8. PMID: 17691059.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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