Description
GTPL-5846 activates GPR84, exhibiting pro-inflammatory activity. This compound increases chemotaxis of polymorphonuclear leukocytes and macrophages and stimulates production of pro-inflammatory cytokines.
Product Info
| Cas No. | 83797-69-7 |
|---|---|
| Purity | ≥98% |
| Formula | C12H21N3O2 |
| Formula Wt. | 239.32 |
| IUPAC Name | 6-(Octylamino)-2,4(1H,3H)-pyrimidinedione |
| Synonym | 6-n-octylaminouracil, 6-OAU |
| Solubility | DMSO: < 7 mg/mL |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Suzuki M, Takaishi S, Nagasaki M, et al. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor. J Biol Chem. 2013 Apr 12;288(15):10684-91. PMID: 23449982.