• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Didymin

Didymin

Product ID D3215
Cas No. 14259-47-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $184.70 In stock
5 mg $729.40 In stock
10 mg $1,085.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Didymin is a flavonoid glycoside found in citrus fruits that displays antioxidative and anticancer chemotherapeutic activities. In cellular and animal models of non-small cell lung cancer (NSCLC), didymin induces Fas-mediated apoptosis and delays tumor growth. Additionally, didymin downregulates PI3K, pAkt, Akt, and vimentin expression and decreases levels of CDK4, n-Myc, and cyclins B1 and D1 in vitro. In animal models of neuroblastoma, didymin decreases tumor size.

Product Info

Cas No.

14259-47-3

Purity

≥98%

Formula

C28H34O14

Formula Wt.

594.56

Chemical Name

Isosakuranetin-7-O-rutinoside

IUPAC Name

5-hydroxy-2-(4-methoxyphenyl)-7-[3,4,5-trihydroxy-6-[(3,4, 5-trihydroxy-6-methyloxan-2-yl)oxymethyl]oxan-2-yl]oxy-2, 3-dihydrochromen-4-one

Synonym

(S)-5,7-Dihydroxy-4′-methoxyflavanone-7-β-rutinoside Isosakuranetin

Solubility

MeOH

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

D3215 MSDS PDF

Info Sheet

D3215 Info Sheet PDF

References

Singhal J, Nagaprashantha LD, Vatsyayan R, et al. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma. Cancer Prev Res (Phila). 2012 Mar;5(3):473-83. PMID: 22174364.

Hung JY, Hsu YL, Ko YC, et al. Didymin, a dietary flavonoid glycoside from citrus fruits, induces Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivo. Lung Cancer. 2010 Jun;68(3):366-74. PMID: 19733932.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N1873

    Nesiritide Acetate

    Recombinant BNP, cardiomodulatory peptide; NPR-...

    ≥95%
  • A4445

    Allopurinol

    Purine (hypoxanthine) analog; xanthine oxidase ...

    ≥98%
  • E537331

    Enniatin Complex

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • O4417

    Oleanolic Acid

    Triterpenoid found in Vigna angularis and Trigo...

    ≥98%
  • T6903

    Tranylcypromine Hydrochloride

    MAO and histone demethylase LSD1 inhibitor.

    ≥98%
  • H014458

    Halometasone

    Glucocorticoid

    ≥98%
  • T0096

    Cephalomannine

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • I0518

    I-BET-762

    BRD inhibitor.

    ≥98%
  • O7053

    L-Ornithine Hydrochloride

    Non-proteinogenic amino acid, L-arginine metabo...

    ≥98%
  • M1976

    Methimazole

    Thioamide; thyroid peroxidase inhibitor.

    ≥98%
  • M1746

    Melphalan

    Nitrogen mustard, DNA alkylator.

    ≥95%
  • T1675

    Teriparatide Acetate

    Synthetic peptide hormone, PTH analog; PTH1R ag...

    ≥95%
  • G1646

    Geldanamycin

    HSP90 inhibitor.

    ≥97%
  • L0226

    Lagochiline

    Diterpene alkaloid found in Lagochilus.

    ≥98%
  • T9945

    Tylosin Tartrate

    Macrolide; peptidyl transferase inhibitor, prot...

    ≥90%
  • M1649

    Melanoma-associated Antigen Peptide 1 (27-35), human

    Melanoma-associated antigen.

    ≥95%
  • R2711

    Recombinant HCV-Core Antigens

    Recombinant HIV core protein antigen fragment.<...

    ≥95%
  • E9819

    Ezetimibe

    NPC1L1 inhibitor.

    ≥99%
  • A9912

    AZD-7762 Hydrochloride

    CHK1 inhibitor.

    ≥98%
  • D1722

    Defactinib

    FAK inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only