LKT Labs

Biochemicals for Life Science Research

Ecdysterone

Ecdysterone

Product ID E0813
Cas No. 5289-74-7
Purity ≥96%
Product Unit SizeCostQuantityStock
5 mg $102.00 In stock
10 mg $143.00 In stock
25 mg $276.00 In stock
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Description

Ecdysterone is a steroid hormone initially produced by arthropods that controls ecdysis and metamorphosis. Ecdysterone binds the ecdysone receptor. This compound induces autophagy and caspase activity during larval-prepupal transition periods in Drosophila. In mammals, ecdysterone may exhibit anabolic activity, decreasing chronic fatigue of nerves and muscles. Ecdysterone may also exhibit pro-angiogenic activity, increasing microvessel density and enhancing angiogenesis in models of cerebral ischemia.

Product Info

Cas No.

5289-74-7
Purity

≥96%
Formula

C27H44O7
Formula Wt.

480.64
Chemical Name

(2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest- 7-en-6-one
IUPAC Name

(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R, 3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16, 17-decahydro-1H-cyclopenta[a]phenanthren-6-one
Synonym

20-Hydroxyecdysone, Crustecdysone, Isoinokosterone, Polypodine A
Melting Point

242-244°C

Solubility

Soluble in alcohol.

Appearance

White Powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

E0813 MSDS PDF
Info Sheet

E0813 Info Sheet PDF

References

Liu H, Jia Q, Tettamanti G, et al. Balancing crosstalk between 20-hydroxyecdysone-induced autophagy and caspase activity in the fat body during Drosophila larval-prepupal transition. Insect Biochem Mol Biol. 2013 Nov;43(11):1068-78. PMID: 24036278.

Volodin VV, Sidorova IuS, Mazo VK. 20-Hydroxyecdysone--plant adaptogen: an anabolic effect, possible use in sports nutrition. Vopr Pitan. 2013;82(6):24-30. PMID: 24741953.

Luo C, Yi B, Fan W, et al. Enhanced angiogenesis and astrocyte activation by ecdysterone treatment in a focal cerebral ischemia rat model. Acta Neurochir Suppl. 2011;110(Pt 1):151-5. PMID: 21116931.

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