• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Etoricoxib

Etoricoxib

Product ID E7858
Cas No. 202409-33-4
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $63.00 In stock
25 mg $89.30 In stock
100 mg $257.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, antioxidative, anticancer, anti-angiogenic, and chemopreventive activities. Etoricoxib inhibits COX-2; it also increases activity of superoxide dismutase, catalase, glutathione reductase, and glutathione transferase in animal models. Etoricoxib downregulates expression of matrix metalloproteinases 2 and 9 (MMP2/9), COX-2, MPC-1, VEGF, and MIP-1β in vivo. In other animal models, etoricoxib decreases aberrant crypt foci and lesion formation, suppressing colon carcinogenesis.

Product Info

Cas No.

202409-33-4

Purity

≥99%

Formula

C18H15ClN2O2S

Formula Wt.

358.84

IUPAC Name

5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine

Solubility

freely soluble in methanol, tetrahydrofuran, dimethyl sulfoxide, methyl ethyl ketone, dimethyl formamide, and chloroform. Etoricoxib is soluble in isopropyl acetate, ethanol and toluene, sparingly soluble in 2-propanol, and practically insoluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E7858 MSDS PDF

Info Sheet

E7858 Info Sheet PDF

Brochures

NSAID Flyer

References

Nadda N, Vaish V, Setia S, et al. Angiostatic role of the selective cyclooxygenase-2 inhibitor etoricoxib (MK0663) in experimental lung cancer. Biomed Pharmacother. 2012 Sep;66(6):474-83. PMID: 22681911.

Sharma P, Kaur J, Sanyal SN. Effect of etoricoxib, a cyclooxygenase-2 selective inhibitor on aberrant crypt formation and apoptosis in 1,2 dimethyl hydrazine induced colon carcinogenesis in rat model. Nutr Hosp. 2010 Jan-Feb;25(1):39-48. PMID: 20204254.

Kanwar SS, Vaiphei K, Nehru B, et al. Antioxidative effects of nonsteroidal anti-inflammatory drugs during the initiation stages of experimental colon carcinogenesis in rats. J Environ Pathol Toxicol Oncol. 2008;27(2):89-100. PMID: 18540845.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R2514

    RGDV

    Tretraeptide, binds cell surface integrins.

    ≥98%
  • N6076

    N(p-Tosyl)-GPR-pNA

    Thrombin substrate used to measure thrombin act...

    ≥95%
  • A4679

    Altrenogest

    Synthetic progestogen; PR agonist.

    ≥98%
  • C0249

    Calcitonin Gene Related Peptide (8-37), rat

    Endogenous calcitonin-family peptide frgament, ...

    ≥95%
  • A5039

    Amitraz

    Insecticide; α-adrenergic agonist, MAO inhibit...

    ≥97%
  • U6858

    Urocortin II, mouse

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • C0344

    Calphostin C

    Found in Cladosporium; PKC inhibitor.

    ≥95%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • H9763

    Hypoxanthine

    Endogenous purine derivative of xanthine.

    ≥98%
  • S8045

    S-Sulforaphane

    Synthetic antioxidant that induces phase II enz...

    ≥96%
  • M5675

    Motilin, canine

    Endogenous peptide hormone; motilin agonist.

    ≥95%
  • R8179

    Rutaecarpine, synthetic

    Found in Evodia rutaecarpa; potential cAMP, 3β...

    ≥98%
  • C086007

    CC-671

    TTK/CLK2 inhibitor.

    ≥98%
  • D183744

    Destruxin A

    Cyclic depsipeptide is a secondary metabolite i...

    ≥98%
  • T1754

    Tenatoprazole

    H+/K+ ATPase inhibitor.

    ≥98%
  • D5690

    Doxazosin Mesylate

    Quinazoline; α1-adrenergic antagonist.

    ≥98%
  • C4517

    Clenbuterol Hydrochloride

    β2-adrenergic agonist.

    ≥98%
  • A4606

    Albendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥95%
  • T0097

    10-Deacetyltaxol B

    Diterpene found in Taxus; potential microtubule...

    ≥98%
  • R0020

    RAF265

    B-Raf, VEGFR2, c-Raf, PDGFR, CSF-1R, RET, c-Kit...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only