• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Febuxostat

Febuxostat

Product ID F1607
Cas No. 144060-53-7
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $54.60 In stock
250 mg $107.80 In stock
1 g $287.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Febuxostat displays a variety of beneficial properties, including anti-inflammatory, anti-hyperuricemic, antidepressant, and nephroprotective activities. Febuxostat inhibits xanthine oxidase, preventing the generation of uric acid; as a result, it is used clinically to treat gout. In vitro, febuxostat inhibits MCP-1 and ROS production through activation of MAPK phosphatase. In vivo, febuxostat decreases oxidative stress and endoplasmic reticular stress, preventing increases in serum creatine and occurrence of renal tubular injury and fibrosis during renal ischemia. Additionally, this compound decreased immobility time during a forced swim test in animal models of depression.

Product Info

Cas No.

144060-53-7

Purity

≥98%

Formula

C16H16N2O3S

Formula Wt.

316.37

Chemical Name

2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid

IUPAC Name

2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F1607 MSDS PDF

Info Sheet

F1607 Info Sheet PDF

References

Nomura J, Busso N, Ives A, et al. Febuxostat, an Inhibitor of Xanthine Oxidase, Suppresses Lipopolysaccharide-Induced MCP-1 Production via MAPK Phosphatase-1-Mediated Inactivation of JNK. PLoS One. 2013 Sep 25;8(9):e75527. PMID: 24086554.

Karve AV, Jagtiani SS, Chitnis KA. Evaluation of effect of allopurinol and febuxostat in behavioral model of depression in mice. Indian J Pharmacol. 2013 May-Jun;45(3):244-7. PMID: 23833366.

Tsuda H, Kawada N, Kaimori JY, et al. Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress. Biochem Biophys Res Commun. 2012 Oct 19;427(2):266-72. PMID: 22995295.

Bisht M, Bist SS. Febuxostat: a novel agent for management of hyperuricemia in gout. Indian J Pharm Sci. 2011 Nov;73(6):597-600. PMID: 23112391.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N5655

    Nonoxynol-9

    Nonoxynol surfactant.

    90-110%
  • C3214

    CID-797718

    Potential PKD binding agent.

    ≥99%
  • M9644

    Myelin Basic Protein (87-99), guinea pig/human

    Immunodominant peptide epitope occurring in mul...

    ≥95%
  • N5766

    L-(-)-Norepinephrine Bitartrate Monohydrate

    Endogenous hormone and neurotransmitter involve...

    ≥98%
  • E5202

    Enalapril

    ACE inhibitor.

    ≥98%
  • B560000

    RAD51 inhibitor, B02

    RAD51 inhibitor.

    ≥98%
  • P200000

    PF-3845

    FAAH inhibitor.

    ≥98%
  • C691325

    Cridanimod

    STING agonist

    ≥99%
  • D3304

    Dibenzoylmethane, 98%

    Aromatic 1,3-diketone acetylacetone derivative ...

    ≥98%
  • G2869

    Ghrelin, rat

    Endogenous peptide hormone, involved in feeding...

    ≥95%
  • H9620

    7-Hydroxyaristolochic Acid A

    Derivative of aristolochic acid found in Asarum...

    ≥95%
  • X0384

    XAV-939

    Tankyrase inhibitor.

    ≥98%
  • G7241

    GSK-461364

    PLK1 inhibitor.

    ≥99%
  • T7036

    Triptorelin

    Peptide, GnRH analog; GnRH agonist.

    ≥98%
  • B6801

    Brassinin

    Phytoalexin, indole found in cruciferous vegeta...

    ≥98%
  • D3462

    Diphenhydramine Hydrochloride

    Voltage-gated Na+ channel blocker, mAChR antago...

    ≥98%
  • T5608

    α-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • G346851

    Givinostat Hydrochloride

    Non-selective HDAC inhibitor.

    ≥98%
  • V0148

    Valproic Acid

    T-type Ca2+ and voltage-gated Na+ channel block...

    ≥98%
  • M177521

    Menaquinone-7

    2-methyl-1,4-naphthoquinone derivative

    98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only