• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Foscarnet Sodium Hydrate

Foscarnet Sodium Hydrate

Product ID F5873
Cas No. 34156-56-4
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $126.50 In stock
5 g $493.00 In stock
10 g $845.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Foscarnet is an antiviral compound that inhibits reverse transcriptase of HIV-1 and DNA polymerase of other viruses, including CMV and HSV. Inhibition of these enzymes prevents DNA synthesis and viral replication. Foscarnet chelates with metal ions and also mimics the pyrophosphate leaving group in DNA polymerase, inducing a closed/un-translocated conformational state. Additionally, foscarnet inhibits type II inorganic phosphate (Pi) transporters in smooth muscle cells, inhibiting Ca2+ deposition and vascular calcification.

Product Info

Cas No.

34156-56-4

Purity

≥98%

Formula

CNa3O5P • 6H2O

Formula Wt.

300.04

Chemical Name

Foscarnet Sodium Hexahydrate

IUPAC Name

trisodium;phosphonatoformate

Synonym

Phosphonoformic acid sodium salt hydrate; Trisodium phosphonoformate, Foscavir

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F5873 MSDS PDF

Info Sheet

F5873 Info Sheet PDF

References

Zahn KE, Tchesnokov EP, Götte M, et al. Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. J Biol Chem. 2011 Jul 15;286(28):25246-55. PMID: 21566148.

Villa-Bellosta R, Sorribas V. Phosphonoformic acid prevents vascular smooth muscle cell calcification by inhibiting calcium-phosphate deposition. Arterioscler Thromb Vasc Biol. 2009 May;29(5):761-6. PMID: 19213941.

Marchand B, Tchesnokov EP, Götte M. The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation. J Biol Chem. 2007 Feb 2;282(5):3337-46. PMID: 17145704.

Morfin F, Thouvenot D. Herpes simplex virus resistance to antiviral drugs. J Clin Virol. 2003 Jan;26(1):29-37. PMID: 12589832.

Hardy WD. Foscarnet treatment of acyclovir-resistant herpes simplex virus infection in patients with acquired immunodeficiency syndrome: preliminary results of a controlled, randomized, regimen-comparative trial. Am J Med. 1992 Feb 14;92(2A):30S-35S. PMID: 1531285.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M2076

    Metformin Hydrochloride

    AMPK activator.

    ≥98%
  • C691325

    Cridanimod

    STING agonist

    ≥99%
  • B8074

    3-tert-Butyl-5-Methoxy-1,2-quinone

    BHA derivative.

    ≥98%
  • E5201

    Enalapril Maleate

    ACE inhibitor.

    ≥98%
  • I058584

    Ibotenic Acid

    Analog of glutamate

    ≥98%
  • P8118

    Puerarin

    Isoflavone daidzein derivative found in Puerari...

    ≥96%
  • R2514

    RGDV

    Tretraeptide, binds cell surface integrins.

    ≥98%
  • G1646

    Geldanamycin

    HSP90 inhibitor.

    ≥97%
  • M4454

    MLN-4924

    Nedd8-activating enzyme inhibitor.

    ≥99%
  • K0054

    Kanamycin B

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • B030962

    BAY-1251152

    Inhibitor of PTEFb/CDK9.

    ≥98%
  • G062680

    GBR-12909 Dihydrochloride

    Dopamine reuptake inhibitor (DRI).

    ≥98%
  • P7103

    Praziquantel

    Alters membrane permeability and Ca2+ signaling...

    ≥98%
  • D3575

    2,5-Di-tert-butyl-4-hydroxyanisole

    BHA derivative; potential Ca2+ ATPase inhibitor...

    ≥98%
  • A4803

    Amantadine Sulfate

    Viral M2 proton channel blocker, MAO-A, NET, NM...

    ≥98%
  • V0145

    Valinomycin

    Peptide, neutral ionophore.

    ≥98%
  • F8151

    Fumonisin B3

    Mycotoxin produced by Fusarium fungi that infec...

    ≥98%
  • T5605

    Tobramycin Sulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • G1849

    Gemifloxacin Mesylate

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥99%
  • T0153

    Tanshinone I

    Diterpene found in Salvia.

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only