• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Fosfomycin Calcium

Fosfomycin Calcium

Product ID F5874
Cas No. 26016-98-8
Purity ≥95%
Product Unit SizeCostQuantityStock
250 mg $52.50 In stock
1 g $67.80 In stock
5 g $141.00 In stock
25 g $563.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fosfomycin is an antibiotic initially produced by Streptomyces that exhibits antibacterial, anti-parasitic, antimalarial, and nephroprotective activities. Fosfomycin is active against both gram positive and gram negative bacteria and acts by inhibiting MurA and preventing synthesis of bacterial cell walls. Fosfomycin also inhibits isopentenyl phosphate kinase, an enzyme in the archaeal mevalonate pathway. In vivo, fosfomycin inhibits iron release from the mitochondria, inhibiting lipid peroxidation and preventing aminoglycoside antibiotic-induced nephrotoxicity. This compound also displays some anti-inflammatory benefit, decreasing serum levels of TNF-α, IL-1β, and IL-6 in animal models of septic Pseudomonas infection, increasing survival rates.

Product Info

Cas No.

26016-98-8

Purity

≥95%

Formula

C3H5CaO4P

Formula Wt.

176.12

IUPAC Name

calcium;(3-methyloxiran-2-yl)-dioxido-oxo-λ5-phosphane

Synonym

MK-0955 calcium

Appearance

White Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F5874 MSDS PDF

Info Sheet

F5874 Info Sheet PDF

References

Olesen SH, Ingles DJ, Yang Y, et al. Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin. J Basic Microbiol. 2013 May 20. [Epub ahead of print]. PMID: 23686727.

Mabanglo MF, Serohijos AW, Poulter CD. The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase. Biochemistry. 2012 Jan 31;51(4):917-25. PMID: 22148590.

Yanagida C, Ito K, Komiya I, et al. Protective effect of fosfomycin on gentamicin-induced lipid peroxidation of rat renal tissue. Chem Biol Interact. 2004 Jul 20;148(3):139-47. PMID: 15276870.

Borrmann S, Adegnika AA, Matsiegui PB, et al. Fosmidomycin-clindamycin for Plasmodium falciparum Infections in African children. J Infect Dis. 2004 Mar 1;189(5):901-8. PMID: 14976608.

Matsumoto T, Tateda K, Miyazaki S, et al. Immunomodulating effect of fosfomycin on gut-derived sepsis caused by Pseudomonas aeruginosa in mice. Antimicrob Agents Chemother. 1997 Feb;41(2):308-13. PMID: 9021184.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F465817

    Flunisolide

    Corticosteroid

    ≥90%
  • P2918

    Phenylethyl-4-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥98%
  • B7973

    Busulfan

    Alkyl sulfonate; DNA alkylator.

    ≥98%
  • X4402

    XL-147

    Dual inhibitor of PI3K and mTOR.

    ≥98%
  • H9812

    5-Hydroxytryptophol

    Serotonin/melatonin analog found in various pla...

    ≥98%
  • A1369

    Adrenomedullin (13-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%
  • M3379

    Mitoxantrone Dihydrochloride

    Anthracenedione, DNA intercalator; Pim-1 inhibi...

    ≥98%
  • U8000

    U-74389G

    Antioxidant shown to improve renal function.

    ≥95%
  • T0104

    Taxol Side Chain Methyl Ester

    Side chain attached to various taxanes.

    ≥96%
  • T1679

    Tetracycline Hydrochloride

    Polyketide; protein translation inhibitor, mamm...

    ≥95%
  • P0001

    P1 Peptide

    Octapeptide, prevents EGFR-PLCγ association.

    ≥95%
  • S4932

    SMI-4a

    Thiazolidine; Pim kinase inhibitor.

    ≥99%
  • I5313

    Indinavir Sulfate

    HIV protease, GLUT4, calpain inhibitor.

    ≥99%
  • A5315

    Deoxyandrographolide

    Labdane diterpene found in Andrographolis; cNOS...

    ≥98%
  • E7329

    Ethoxyquin

    Quinoline, food preservative; HSP90 inhibitor.<...

    ≥90%
  • T2817

    Theophylline

    Methylxanthine; PDE inhibitor, A1/2 adenosine a...

    ≥98%
  • D5992

    Doxapram Hydrochloride Hydrate

    K+ channel blocker, catecholamine release stimu...

    ≥98%
  • A5035

    5-Aminosalicylic Acid

    Salicylic acid derivative; PPARγ agonist, pote...

    ≥98%
  • L961000

    LY-3295668

    Aurora kinase A inhibitor

    ≥99%
  • I7757

    Itopride Hydrochloride

    AChE inhibitor, D2 antagonist.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only