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Fosinopril Sodium

Fosinopril Sodium

Product ID F5773
Cas No. 88889-14-9
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $98.60 In stock
100 mg $338.00 In stock
250 mg $676.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fosinopril is an inhibitor of angiotensin-converting enzyme (ACE) that exhibits antihypertensive and anti-atherosclerotic activities. Fosinopril is clinically used to treat congestive heart failure (CHF). In vivo, fosinopril decreases expression of toll-like receptor 4 (TLR 4) and NF-κB, suppressing formation of atherosclerotic plaques. Additionally, fosinopril decreases left ventricular hypertrophy, pressure, and expression of TGF-β1 in spontaneously hypertensive rats.

Product Info

Cas No.

88889-14-9

Purity

≥98%

Formula

C30H45NNaO7P

Formula Wt.

585.64

IUPAC Name

sodium;(2S, 4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl) phosphoryl]acetyl]pyrrolidine-2-carboxylate

Synonym

Dynacil, Eliten, Fosinil, Fosinopril sodium, Fosinorm, Fosipres, Fositen, Fositens, Foziretic, Fucithalmic, Hiperlex, Monopril, Newace, Sapril, Staril, Tenso Stop, Tensogard

Melting Point

196-198°C

Appearance

White crystalline powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

F5773 MSDS PDF

Info Sheet

F5773 Info Sheet PDF

References

Yang S, Li R, Tang L, et al. TLR4-mediated anti-atherosclerosis mechanisms of angiotensin-converting enzyme inhibitor--fosinopril. Cell Immunol. 2013 Sep-Oct;285(1-2):38-41. PMID: 24044965.

Huang K, Dai G. The effect and mechanism of forsinopril on ventricular hypertrophy of SHR and left ventricular pressure overloading rat. J Huazhong Univ Sci Technolog Med Sci. 2002;22(1):17-20. PMID: 12658773.

Custom Order

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  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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