• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Histatin 5

Histatin 5

Product ID H3273
Cas No. 115966-68-2
Purity ≥95%
Product Unit SizeCostQuantityStock
0.5 mg $147.00 In stock
1 mg $262.50 In stock
2.5 mg $525.00 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Histatin 5 is an endogenous antimicrobial peptide (AMP) present in the salivary gland. Histatin 5 exhibits anti-inflammatory, antibacterial, and antifungal activities. In myeloid dendritic cells, histatin 5 binds Poryphyromonas hemagglutinin B, inhibiting production of MIP-1α, MIP-1β, and TNF-α. Histatin binds bacterial DNA, displaying bactericidal activity against gram positive bacteria such as Streptococcus. Additionally, histatin 5 causes ion flux-induced cell death of Candida cells in an ex vivo model of oral candidiasis.

Product Info

Cas No.

115966-68-2

Purity

≥95%

Formula

C133H195N51O33

Formula Wt.

3036.36

Solubility

Soluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

H3273 MSDS PDF

Info Sheet

H3273 Info Sheet PDF

References

Borgwardt DS, Martin AD, Van Hemert JR, et al. Histatin 5 binds to Porphyromonas gingivalis hemagglutinin B (HagB) and alters HagB-induced chemokine responses. Sci Rep. 2014 Jan 29;4:3904. PMID: 24473528.

Huo L, Zhang K, Ling J, et al. Antimicrobial and DNA-binding activities of the peptide fragments of human lactoferrin and histatin 5 against Streptococcus mutans. Arch Oral Biol. 2011 Sep;56(9):869-76. PMID: 21382611.

Peters BM, Zhu J, Fidel PL Jr, et al. Protection of the oral mucosa by salivary histatin-5 against Candida albicans in an ex vivo murine model of oral infection. FEMS Yeast Res. 2010 Aug 1;10(5):597-604. PMID: 20491938.

Jang WS, Bajwa JS, Sun JN, et al. Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans. Mol Microbiol. 2010 Jul;77(2):354-70. PMID: 20487276.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N8760

    NVP-TAE684

    ALK, c-Fes, LRRK2 inhibitor.

    ≥98%
  • N1769

    Nerolidol, synthetic

    AChE inhibitor, F0F1-ATP synthase modulator.

    A mixture of cis and trans isomers, ≥96%
  • C5647

    Colistin Sulfate

    Polymixin, antimicrobial peptide, induces forma...

    Biological Potency: ≥19366 IU/mg
  • A5378

    Antimycin A

    Oxidative phosphorylation inhibitor.

  • A9603

    5-Aza-2′-deoxycytidine

    Nucleoside (deoxycytidine) analog; DNMT inhibit...

    ≥98%
  • O4549

    Olmesartan Medoxomil

    AT1 inhibitor.

    ≥98%
  • R8122

    Rufloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • L1884

    Levosimendan

    Ca2+ sensitizer; ATP-sensitive K+ channel activ...

    ≥98%
  • C1648

    α-Cembrenediol

    Diterpene found in Anisomeles.

    ≥99%
  • G7862

    GTPL-5846

    GPR84 agonist.

    ≥98%
  • A0820

    N-Acetyl-S-(N′-benzylthiocarbamoyl)-L-cysteine

    Cysteine-ITC conjugate, BITC derivative, antiox...

    ≥98%
  • R8178

    Rutaecarpine

    Indoloquinazoline alkaloid found in Evodia; COX...

    ≥98%
  • G016499

    2’,3’-cGAMP Sodium Salt

    Agonist of STING.

    ≥99%
  • T0090

    7-(Triethylsilyl)-baccatin III

    Synthetic taxol synthesis intermediate; microtu...

    ≥98%
  • L1340

    LDK378

    ALK and IGF-1R inhibitor.

    ≥99%
  • N0114

    Nadifloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • P7103

    Praziquantel

    Alters membrane permeability and Ca2+ signaling...

    ≥98%
  • B8070

    2-tert-Butyl-4-Hydroxyanisole

    BHA derivative, antioxidative food and cosmetic...

    ≥99% single isomer
  • H5654

    Honokiol

    Lignan found in species of Magnolia; GABA-A pot...

    ≥99%
  • R1776

    Resveratrol

    Phenolic phytoalexin found in soy, grapes, and ...

    ≥99%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only