• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Fulvestrant

Fulvestrant

Product ID F8147
Cas No. 129453-61-8
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $71.50 In stock
25 mg $204.30 In stock
100 mg $612.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fulvestrant is an anti-endocrine compound that exhibits anticancer chemotherapeutic benefit in the treatment of estrogen receptor (ER)-positive breast cancer. Fulvestrant causes degradation of ERs and downregulates ER expression, inhibiting cell growth. Fulvestrant also upregulates expression of UDP glucoronosyltransferase 1A4 (UGT1A4) in cancer cells. Additionally, fulvestrant exhibits some anti-hyperlipidemic benefit in clinical settings, as patients receiving it as a chemotherapeutic also exhibited lower serum levels of total cholesterol and LDL.

Product Info

Cas No.

129453-61-8

Purity

≥98%

Formula

C32H47F5O3S

Formula Wt.

606.77

Chemical Name

(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

IUPAC Name

(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5, 5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Synonym

Faslodex

Solubility

Soluble in ethanol (>200 mg/mL), DMSO (>20 mg/mL). Insoluble in water. DMF 20 mg/mL, chloroform.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F8147 MSDS PDF

Info Sheet

F8147 Info Sheet PDF

References

Edavana VK, Penney RB, Yao-Borengasser A, et al. Fulvestrant up regulates UGT1A4 and MRPs through ERα and c-Myb pathways: a possible primary drug disposition mechanism. Springerplus. 2013 Nov 20;2:620. PMID: 24298433.

Krell J, Januszewski A, Yan K, et al. Role of fulvestrant in the management of postmenopausal breast cancer. Expert Rev Anticancer Ther. 2011 Nov;11(11):1641-52. PMID: 22050013.

Scott SM, Brown M, Come SE. Emerging data on the efficacy and safety of fulvestrant, a unique antiestrogen therapy for advanced breast cancer. Expert Opin Drug Saf. 2011 Sep;10(5):819-26. PMID: 21699443

Camerini A, Rondini M, Garrone O, et al. Fulvestrant treatment is associated with cholesterol plasma level reduction in hormone-receptor-positive metastatic breast cancer patients. Cancer Biol Ther. 2009 Aug;8(15):1450-5. PMID: 19556864.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • G6803

    Granuliberin R

    Antimicrobial peptide found in amphibians.

    ≥95%
  • B3210

    R-Bicalutamide

    AR antagonist.

    ≥98%
  • A9710

    AZD-2014

    mTOR inhibitor.

    ≥98%
  • P0369

    Parecoxib Sodium

    NSAID; COX-2 inhibitor.

    ≥99%
  • P6958

    Protopanaxatriol

    Triterpene sapogenin found in species of Panax;...

    ≥95%
  • A0961

    Adrenocorticotropic Hormone (1-39), rat

    Endogenous peptide hormone, involved in stress ...

    ≥95%
  • A016495

    5-Aminopyrimidine

    Building block

    ≥98%
  • M4100

    MK-0524

    DP1 antagonist.

    ≥99%
  • B3203

    Biapenem

    β-lactam; penicillin binding protein inhibitor...

    ≥98%
  • H9802

    Hyaluronic Acid Sodium (7-10 kDA)

    Glycosaminoglycan

  • P0253

    Panaxadiol

    Triterpene sapongenin found in species of Panax...

    ≥98%
  • P1202

    PD-325901

    MEK1/2 and Raf inhibitor.

    ≥99%
  • C0378

    Catharanthine Tartrate

    Alkaloid found in Catharanthus, precursor in sy...

    ≥97%
  • E6825

    Ergosterol

    Sterol cell membrane component found in yeast a...

    ≥96%
  • P7318

    Pseudoginsenoside F11

    Saponin found in species of Panax; PPARγ agoni...

    ≥98%
  • T286161

    Theaflavin

    Polyphenolic compound present in black tea.

    ≥98%
  • D183745

    Destruxin B

    Cyclic depsipeptide is a secondary metabolite i...

    ≥96%
  • Z4552

    ZLN005

    PPARγ coactivator-1α expression stimulator.

    ≥98%
  • J0379

    Jatrorrhizine Chloride

    Alkaloid compound originally found in Corydalis...

    ≥95%
  • P1200

    PD-184352

    MEK1/2 and Raf inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only