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Ganciclovir

Ganciclovir

Product ID G0152
Cas No. 82410-32-0
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $75.10 In stock
100 mg $135.10 In stock
500 mg $374.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ganciclovir is a guanosine nucleoside analog that exhibits antiviral activity. Ganciclovir is clinically used to treat cytomegalovirus infection; it inhibits viral DNA polymerase and acts as a chain terminator when incorporated into DNA, limiting DNA synthesis. Ganciclovir is often co-administered with HSV thymidine kinase gene therapy as a sensitizer.

Product Info

Cas No.

82410-32-0

Purity

≥98%

Formula

C9H13N5O4

Formula Wt.

255.23

Chemical Name

2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]- methyl]-6H-purin-6-one

IUPAC Name

2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one

Synonym

DHPG, 2'NDG, BIOLF

Melting Point

250°C (dec)

Solubility

Soluble in water (2 mg/mL), 0.1 M HCl (10 mg/mL), DMSO (5 mg/mL), ethanol (<1 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G0152 MSDS PDF

Info Sheet

G0152 Info Sheet PDF

References

Prichard MN, Kern ER. The search for new therapies for human cytomegalovirus infections. Virus Res. 2011 May;157(2):212-21. PMID: 21095209.

Abate-Daga D, Garcia-Rodríguez L, Sumoy L, et al. Cell cycle control pathways act as conditioning factors for TK/GCV sensitivity in pancreatic cancer cells. Biochim Biophys Acta. 2010 Oct;1803(10):1175-85. PMID: 20599444.

De Clercq E, Neyts J. Antiviral agents acting as DNA or RNA chain terminators. Handb Exp Pharmacol. 2009;(189):53-84. PMID: 19048197.

Custom Order

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