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Gastrin Releasing Peptide, human

Gastrin Releasing Peptide, human

Product ID G0181
Cas No. 93755-85-2
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $126.00 In stock
2.5 mg $252.00 In stock
5 mg $446.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Gastrin-releasing peptide (BB2) is an endogenous bombesin-like peptide that stimulates the release of gastrin by binding BB2 receptors; it is involved in feeding behavior (acting as an anorexigenic), circadian rhythms, and stress signaling. BB2 induces scratching behavior in vivo and exhibits pro-angiogenic activity in cancer models, inducing expression of IL-8 in a hepatocyte growth factor-dependent manner in gastric cancer cells.

Product Info

Cas No.

93755-85-2

Purity

≥95%

Formula

C130H204N38O31S2

Formula Wt.

2859.40

Synonym

GRP

Solubility

Soluble in water (1 mg/mL), DMSO.

Appearance

White to off-white Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G0181 MSDS PDF

Info Sheet

G0181 Info Sheet PDF

References

Kallingal GJ, Mintz EM. Site-specific effects of gastrin-releasing peptide in the suprachiasmatic nucleus. Eur J Neurosci. 2014 Feb;39(4):630-9. PMID: 24528136.

Lee KH, Koh SA, Kim JR. Hepatocyte growth factor-mediated gastrin-releasing peptide induces IL-8 expression through Ets-1 in gastric cancer cells. Oncol Res. 2013;20(9):393-402. PMID: 23924923.

Sukhtankar DD, Ko MC. Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice. PLoS One. 2013 Jun 24;8(6):e67422. PMID: 23826298.

Merali Z, McIntosh J, Anisman H. Role of bombesin-related peptides in the control of food intake. Neuropeptides. 1999 Oct;33(5):376-86. PMID: 10657515.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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